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SI9885: PRT-4165

LifeSensors SI9885 (PRT-4165) is a potent inhibitor of histone H2A ubiquitylation, targeting RNF2 and Ring1A in polycomb repressive complex 1 (PRC1), used in epigenetic research.

$122.00

SKU SI-9885-0010 Categories E1-E2-E3 Inhibitors, Small Molecule Modulators and PROTACs

In stock

Product Advantages

Applications

Studying chromatin remodeling

A potent inhibitor of histone H2A ubiquitylation. Inhibits RNF2 and Ring1A, both of which are found in polycomb repressive complex 1 (PRC1). Does not inhibit RNF8 or RNF168. Inhibits accumulation of ubiquitin around DNA double-strand breaks (DSBs) as well as the repair of DSBs.

Info

Purity	> 98% (TLC); NMR (conforms)
Quantity	10 mg
Molecular Weight	235.2 g/mol, alternative Daltons
Physical State	Dry yellow powder
Solubility	DMSO (25mg/mL)
CAS No.	31083-55-3
Storage	4°C, (-20°C Long term). Store solutions at -20°C. The product can be shipped at room temperature.

Datasheet

Datasheet

Applications

Studying chromatin remodeling

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