Questions about a product, technology or experimental design? Give us a call 610-644-8845. For special institutional pricing, check out our Distributors!
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9740: Celastrol

LifeSensors SI9740 is a specialized phospho-ubiquitin chain derivative designed for advanced research in ubiquitin signaling and protein regulation pathways.

Price range: $171.00 through $541.00

Celastrol is a naturally occurring triterpenoid antioxidant compound with anti-inflammatory activity. Inhibits NFκB (IC50 = 270 nM). It induces heat shock response and cytoprotection in various cells. Celastrol inhibits 20S proteasome chymotrypsin-like activity (IC50 = 2.5 μM). Cell permeable.

Info

Purity > 98% (TLC), NMR (Conforms)
Quantity 10 mg, 50 mg
Molecular Weight 450.6 Da
Physical State Red powder
Solubility DMSO (45mg/mL); Ethanol (30mg/mL)
CAS No. 34157-83-0
Storage 4°C, (-20°C Long term). The product can be shipped at room temperature.

Applications

  • Inhibition of NF-kappa-B-dependent pathways and inhibition of 20S proteasome chymotrypsin-like activity
  • Cell biology
  • Drug discovery
  • Benefits: cell-permeable

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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