SI9760: Lactacystin, proteasome inhibitor

Lactacystin is a cell-permeable, potent and selective proteasome inhibitor that binds irreversibly to the catalytic β-subunit of the 20S proteasome inhibiting its chymotrypsin-like and trypsin-like activities. Also known to inhibit NF-κB activation (IC50 = 10 μM).

Info

Purity	> 98% by TLC; NMR (conforms)
Quantity	200 µg
Molecular Weight	376.42 Da
Physical State	White solid
Solubility	Water soluble (10mg/ml), DMSO (20mg/ml)
CAS No.	133343-34-7
Storage	4°C, (-20°C Long term). Store solutions at -20°C for up to one month. The product can be shipped at room temperature.