SI9760: Lactacystin, proteasome inhibitor

$292.16

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Specifications

Lactacystin is a cell-permeable, potent and selective proteasome inhibitor that binds irreversibly to the catalytic β-subunit of the 20S proteasome inhibiting its chymotrypsin-like and trypsin-like activities. Also known to inhibit NF-κB activation (IC50 = 10 μM).

Info

Purity > 98% by TLC; NMR (conforms)
Quantity 200 µg
Molecular Weight 376.42 Da
Physical State White solid
Solubility Water soluble (10mg/ml), DMSO (20mg/ml)
CAS No. 133343-34-7
Storage 4°C, (-20°C Long term). Store solutions at -20°C for up to one month. The product can be shipped at room temperature.

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Applications

  • Inhibition of the 20S proteasome
  • Cell biology
  • Drug discovery
  • Benefits: cell-permeable

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