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SI9689: NSC-632839

LifeSensors SI9689 is a potent, selective inhibitor of USP30 deubiquitinase, used in research to study mitochondrial quality control and neurodegenerative diseases.

$171.00 – $566.00

SKU SI-9689 Categories DUB inhibitors, Small Molecule Modulators and PROTACs

Product Advantages

A pan-specific ubiquitin & ubiquitin-like isopeptidase inhibitor. Inhibits USP2, USP7, and SENP2 with EC50 values of 45 ± 4 μM, 37 ± 1 μM, and 9.8 ± 1.8 μM, respectively. Does not affect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway. Cell permeable.

Info

Purity	>98% (HPLC); NMR (Conforms)
Quantity	10 mg, 50 mg
Molecular Weight	339.9 Da
Physical State	Yellow Powder
Solubility	DMSO (8 mg/mL)
CAS No.	157654-67-6
Storage	4°C, (-20°C Long term). Store solutions at -20°C for up to 1 month. The product can be shipped at room temperature.

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