Questions about a product, technology or experimental design? Give us a call 610-644-8845.

AC2006: 17-DMAG HCl

Lifesensors AC2006 (17-DMAG HCl) is a potent geldanamycin analog that induces apoptosis in tumor cells, used as an autophagy modulator in cancer research.

$52.00 – $211.00

SKU AC-2006 Categories Autophagy Inducers, Autophagy Modulators, Small Molecule Modulators and PROTACs

Product Advantages

Alvespimycin hydrochloride (17-DMAG HCl) is a cell permeable potent HSP90 inhibitor with IC₅₀ of 62 nM in a cell-free assay. 17-DMAG HCl is a geldanamycin analog that displays superior pharmacological properties and induces apoptosis in a variety of tumor cell lines. 17-DMAG HCl also inhibits angiogenesis.

Info

Purity	>98% by TLC
Quantity	1 mg, 5 mg
Molecular Weight	653.2 g/mol
Physical State	Lyophilized purple powder
Solubility	30 mg/ml in DMSO; 10 mg/mL in ethanol
CAS No.	467214-21-7
Storage	-20°C, avoid freeze/thaw cycles

Datasheet

Datasheet

send us a message for pricing

CONTACT INFORMATION

Phone (Office)

610.644.8845

SEND EMAIL

info@lifesensors.com

VISIT ANYTIME

271 Great Valley Parkway Malvern, PA 19355

More from This Category

SI9830: MLN-4924

LifeSensors SI9830 (MLN4924) is a potent, selective substrate-assisted inhibitor of NEDD8-activating enzyme (NAE), used to block neddylation and study protein degradation pathways in drug discovery and cancer research.

SI9840: TAME HCl

LifeSensors SI9840 (TAME HCl) inhibits the anaphase-promoting complex/cyclosome (APC/C), blocking Cdc20 and Cdh1 activation, stabilizing cyclin B1, used in cell-based assays.

SI9629: IU1

LifeSensors SI9629 is a selective, reversible, cell-permeable inhibitor of proteasome-associated DUB USP14 with IC50 below 4 µM, ideal for proteasome research.

AC1003: Chloroquine diphosphate

Lifesensors AC1003 (Chloroquine diphosphate) is a 4-aminoquinoline compound used as an anti-malarial, anti-rheumatoid agent, and ATM activator in research.

PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.

Discovery

About lifesensors

Resources

Address: 271 Great Valley Parkway Malvern, PA 19355