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Questions about a product, technology or experimental design? Give us a call 610-644-8845.
SI9619-5MG PR-619

SI9880: SMER3

LifeSensors SI9880 (SMER3) is a specific inhibitor of the ubiquitin E3 ligase SCFMET30, used in research to modulate protein degradation and ubiquitin pathways.

Price range: $250.00 through $1,246.00

Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor of the ubiquitin E3 ligase SCFMET30. SMER3 binds directly to the F-box subunit Met30 and blocks binding to the SCF core complex. This inhibitor is cell permeable. Significant inhibition is typically seen at 30-100 μM.

Info

Purity >98% (TLC), NMR (conforms)
Quantity 10 mg, 25 mg, 50 mg
Molecular Weight 224.2 g/mol, alternative Daltons
Physical State Yellow powder
Solubility DMSO (20mg/ml), requires heating
CAS No. 67200-34-4
Storage 4°C, (-20°C Long term). Store solutions at -20 °C for up to 2 months. The product can be shipped at room temperature.

Applications

  • Cell-based or in vitro inhibition of SCFMET30

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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