Specifications
Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor of the ubiquitin E3 ligase SCFMET30. SMER3 binds directly to the F-box subunit Met30 and blocks binding to the SCF core complex. This inhibitor is cell permeable. Significant inhibition is typically seen at 30-100 μM.
Info
| Purity | >98% (TLC), NMR (conforms) |
| Quantity | 10 mg, 25 mg, 50 mg |
| Molecular Weight | 224.2 Da |
| Physical State | Yellow powder |
| Solubility | DMSO (20mg/ml), requires heating |
| CAS No. | 67200-34-4 |
| Storage | 4°C, (-20°C Long term). Store solutions at -20 °C for up to 2 months. The product can be shipped at room temperature. |
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