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AC1007: Vinblastine Sulfate

Lifesensors AC1007 (Vinblastine Sulfate) is a potent autophagy inhibitor and small molecule modulator used in research, available in 5 mg and 25 mg quantities.

$75.00 – $269.00

SKU AC-1007 Categories Autophagy Inhibitors, Autophagy Modulators, Small Molecule Modulators and PROTACs

Product Advantages

Autophagy inhibitor: inhibits autophagosome maturation

Vinblastine sulfate is a semisynthetic alkaloidal anticancer agent. It induces cell cycle arrest at G2/M phase by inhibiting mitotic spindle formation. It also inhibits normal microtubule assembly and induces aberrant tubulin polymerization. Vinblastine sulfate induces apoptosis in a variety of cell lines, inhibits autophagosome maturation, and palmitoylation of tubulin. Vinblastine sulfate also suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay.

Info

Purity	98% by TLC
Quantity	5 mg, 25 mg
Molecular Weight	909.1 g/mol
Physical State	Lyophilized white crystalline powder
Solubility	25 mg/mL in DMSO; 50 mg/mL in water
CAS No.	143-67-9
Storage	-20°C, avoid freeze/thaw cycles

Datasheet

Datasheet

Autophagy inhibitor: inhibits autophagosome maturation

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