UB308: Cbl-b Core

SKU UB-0308-0025 Categories E3 Ubiquitin Ligases, Ubiquitin Ligases and Enzymes Tag E3 ligase

LifeSensors UB308 is a recombinant human Cbl-b core protein used in ubiquitin pathway research, enabling studies on E3 ligase activity and protein regulation.

$419.00

In stock

Cbl-b is an E3 ligase which regulates a large number of different signaling molecules in the cell. The Cbl family of proteins share a highly Homologous tyrosine kinase-binding (TKB) domain. The TKB domain is followed by a highly conserved helical linker (L) domain and a RING (really interesting new gene) finger (RF) domain, which bind to ubiquitin-conjugating enzymes (E2). In contrast, the C-terminal regions of this family of proteins are less conserved. This truncated version of Cbl-b contains the TKB and the RF domain only.

Info

Species	Human
Source	E. coli
Tag	His₆+ HA
Molecular Weight	48 kDa
Quantity	25 µg
Concentration	Variable
Formulation
Storage	-80°C, avoid freeze/thaw cycles

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