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UB230: UBE2Z

LifeSensors UB230 (UBE2Z) is a specific E2 ubiquitin conjugating enzyme substrate for Uba6 E1, essential for studying ubiquitin-proteasome pathways in protein regulation research.

$274.00 – $545.00

SKU UB-0230 Categories E2 Ubiquitin Conjugating Enzymes, Ubiquitin Ligases and Enzymes

Product Advantages

Applications

Identify cognate E2/E3 pairs
Characterize upregulation/downregulation of E2 enzymes
Build poly-ubiquitin chains
Characterize ubiquitin chain specificity of E2 enzymes
Analyze expression of E2 enzymes

UBE2Z is a ubiquitin conjugating enzyme (E2) that appears to be a specific substrate for the Uba6 ubiquitin activating enzyme (E1). Little is known about the specific function of this E2, but it has been implicated as a proapoptotic enzyme. The protein has been cited to exist as alternate splice variants, a 354 amino acid form and a 181 amino acid form (isoform 2). LifeSensors currently offers the second isoform.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	28,075.4 Da
Quantity	0.8 nmol, 3.0 nmol
Concentration	40 µM
Formulation	25 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage	-80°C, avoid freeze/thaw cycles

Datasheet

Datasheet

Applications

Identify cognate E2/E3 pairs
Characterize upregulation/downregulation of E2 enzymes
Build poly-ubiquitin chains
Characterize ubiquitin chain specificity of E2 enzymes
Analyze expression of E2 enzymes

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