Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UB216: UBE2F

LifeSensors UB216 is the UBE2F E2 ubiquitin conjugating enzyme, essential for targeted ubiquitylation in protein regulation, available for advanced biochemical research.

Price range: $245.00 through $439.00

UBE2F is an E2 conjugation enzyme that is involved in the ubiquitylation of target substrates, along with E1 and E3 enzymes. UBE2F mediates the transfer of NEDD8 from NEDD8-activating enzyme E1 (UBA3-NAE1 complex) to a substrate protein. This E2 enzyme has been shown to associate with the both NEDD8 E3 ligase and RBX2, yet displays different target cullin specificities than a similar UBE2M/RBX1 E2/E3 complex.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 21,077.4 Da
Quantity 0.8 nmol, 3.0 nmol
Concentration Variable
Formulation 20 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Applications

  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes

Benefits

  • Untagged (native) E2 conjugation enzyme

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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