Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9845: SKPin C1

LifeSensors SI9845 (SKPin C1) is a selective inhibitor of Skp2-mediated p27 degradation, inducing p27 accumulation and cell cycle arrest, used in cancer research and Skp2 studies.

$159.00

In stock

In stock

Inhibits the cullin-RING ubiquitin E3 ligase SCF-Skp2. Selectively inhibits Skp2-mediated p27 degradation by reducing p27 binding. In cancer cells, the compound induces p27 accumulation and promotes cell type-specific blocks in G1 or G2/M phases.

Info

Purity 98% by TLC; NMR (conforms)
Quantity 5 mg
Molecular Weight 465.34 g/mol, alternative Daltons
Physical State Lyophilized solid
Solubility DMSO (58mg/ml); Ethanol (8mg/ml); Water (<1mg/ml)
CAS No. 432001-69-9
Storage Store desiccated as supplied at 4ÂşC; Product can be shipped at room temperature.

Applications

  • Cell-based and in vitro studies of Skp2 function.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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