Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UPS Inhibitor

SI9815: JNJ26854165/Serdemetan

LifeSensors SI9815 is a high-purity ubiquitin protein used in biochemical research to study ubiquitination processes and protein degradation pathways.

$250.00

SKU SI-9815-0005 Categories E1-E2-E3 Inhibitors, Small Molecule Modulators and PROTACs

In stock

Product Advantages

Applications

Cell-based and in vitro studies of hdm2 function

An oral, phase 1 hdm2 antagonist. Binds the RING domain of MDM2 and inhibits survival in cancer cells.

Info

Purity	>99% (TLC), NMR (conforms)
Quantity	5 mg
Molecular Weight	328.41 Da
Physical State	Lyophilized solid
Solubility	DMSO (66mg/ml); Ethanol (<2mg/ml); Water (<1mg/ml)
CAS No.	881202-45-5
Storage	4°C, (-20°C Long term). The product can be shipped at room temperature.

Document 1

Document 1

Applications

Cell-based and in vitro studies of hdm2 function

send us a message for pricing

CONTACT INFORMATION

Phone (Office)

610.644.8845

SEND EMAIL

info@lifesensors.com

VISIT ANYTIME

271 Great Valley Parkway Malvern, PA 19355

More from This Category

SI9890: AT-406

LifeSensors SI9890 (AT-406) is an oral Smac mimetic that inhibits apoptosis proteins XIAP, cIAP1, and cIAP2, showing potential in cancer therapy and currently in phase 1 trials.

AC2006: 17-DMAG HCl

Lifesensors AC2006 (17-DMAG HCl) is a potent geldanamycin analog that induces apoptosis in tumor cells, used as an autophagy modulator in cancer research.

SI9619: PR-619

LifeSensors SI9619 (PR-619) is a cell-permeable, reversible, non-selective inhibitor of deubiquitinases and ubiquitin-like isopeptidases, inducing ubiquitin and SUMO protein accumulation with IC50 of 5-20 µM for cell biology and drug discovery research.

SI9710: MG-132, proteasome inhibitor

LifeSensors SI9710 is a high-quality ubiquitin reagent designed for advanced research in protein degradation and signaling pathways, enhancing studies in ubiquitin biology.

PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.

Discovery

About lifesensors

Resources

Address: 271 Great Valley Parkway Malvern, PA 19355