Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9855: PTC-209

LifeSensors SI9855 (PTC-209) selectively reduces BMI-1 protein levels, impacting chromatin remodeling and gene repression, used for studying BMI-1 function in cancer research.

$225.00

In stock

In stock

Treatment of cells with PTC-209 leads to the selective reduction in the levels of BMI-1 protein (Kreso, van Galen et al. 2014). BMI-1 is a component of the polycomb PRC complex and interacts directly with the E3 ligase RING1A and/or RING2. The PRC complex mediates monoubiquitylation of histone H2A on Lys-119 and is involved in chromatin remodeling and repression of gene expression.

Info

Purity 99%; NMR consistent with structure
Quantity 5 mg
Molecular Weight 576.1 g/mol, alternative Daltons
Physical State Powder
Solubility 173mM in DMSO
CAS No. 1217022-63-3
Storage 4°C, (-20°C Long term). The product can be shipped at room temperature.

Applications

  • Studying the function of BMI-1

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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