Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9850: NSC-66811

LifeSensors SI9850 (NSC-66811) is a cell-permeable, non-peptide inhibitor of MDM2-p53 interaction (Ki=120nM), activating p53 and p21 in cancer cells for research on tumor suppression.

$250.00

In stock

In stock

A cell-permeable, non-peptide inhibitor of MDM2-p53 interactions (Ki=120nM). Treatment of cancer cells activates p53 and accumulation of p21, p53, and MDM2. The structure mimics three p53 residues involved in binding to MDM2.

Info

Purity >97% (TLC, HPLC), NMR (conforms)
Quantity 10 mg
Molecular Weight 340.4 g/mol, alternative Daltons
Physical State White solid
Solubility DMSO (25mg/ml)
CAS No. 6964-62-1
Storage 4°C, (-20°C Long term). The product can be shipped at room temperature.

Applications

  • Cell-based studies of MDM2 and p53 function
  • Comparative studies of new MDM2 or p53 inhibitors

Benefits

  • Cell-permeable
  • Non-peptide inhibitor of MDM2-p53 interactions
  • nM potency

 

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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