Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9720: PS-341

LifeSensors SI9720 is a specialized reagent for ubiquitin-proteasome research, aiding drug discovery with high-quality assays and protein analysis tools.

Price range: $245.00 through $621.00

PS-341 (Pyz-Phe-boroLeu) is the active ingredient in Bortezomib (Velcade). PS-341 is a reversible, cell-permeable, potent, and selective proteasome inhibitor (Ki = 0.6 nM). It binds the catalytic site of the 26S proteasome with high affinity and specificity. Inhibits proliferation of a number of tumor cell lines (IC50 = 7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis.

Info

Purity >98% (HPLC), NMR (conforms)
Quantity 5 mg, 25 mg
Molecular Weight 384.24 Da
Physical State White powder
Solubility DMSO (76 mg/mL)
CAS No. 179324-69-7
Storage 4°C, (-20°C Long term). The product can be shipped at room temperature.

Applications

  • Inhibition of 26S proteasome
  • Cell biology
  • Benefits: cell-permeable

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

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271 Great Valley Parkway Malvern, PA 19355

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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