SI9649: 1,10 phenanthroline

SKU SI-9649-0500 Categories DUB inhibitors, Small Molecule Modulators and PROTACs

LifeSensors SI9649 (1,10-Phenanthroline) is a chelator with high affinity for divalent metal ions, used in biochemical research for metal ion binding and inhibition studies.

$161.00

1,10-phenanthroline (o-phenanthroline) is a chelator with a high affinity for divalent metal ions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn2+ ion. As such, o-phenanthroline is widely used when preparing cell lysates for the enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.

Info

Purity	> 99% (TLC), NMR (conforms)
Quantity	0.5 mL DMSO solution, 100X
Molecular Weight	198.21 Da
Physical State	Liquid
Solubility	DMSO
CAS No.	5144-89-8
Storage	-80°C. The Product can be shipped at room temperature.

This product has been cited 1 time.

Datasheet

Applications

A critical component for protecting K63-linked polyubiquitin chains in cell lysates.

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SI9649: 1,10 phenanthroline

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