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Questions about a product, technology or experimental design? Give us a call 610-644-8845.

PC1005: Pomalidomide

SKU PC-1005 Categories ,
LifeSensors’ PC1005 is a specialized assay kit designed for ubiquitin pathway enzyme research, enabling precise analysis of ubiquitin ligases and deubiquitylases

Price range: $55.00 through $225.00

Pomalidomide is a thalidomide derivative and a potent TNF-α inhibitor (IC50 = 13 nM). It also potently inhibits IL-2 (EC50 = 8 nM).  It binds cereblon and inhibits its ubiquitination. Pomalidomide exhibits antiproliferative effects in a Namalwa lymphoma cell line and is antiangiogenic.

Info

Purity  >95%
Quantity 1mg, 5mg
Molecular Weight 273.24 g/mol
Physical State Lyophilized pale-yellow to yellow-brown solid
Solubility 25 mg/mL in DMSO
CAS No. 19171-19-8
Storage Room Temperature

Pomalidomide is a cereblon ubiquitination inhibitor. It is also a TNF-α inhibitor and antiangiogenic.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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