Specifications
Pomalidomide is a thalidomide derivative and a potent TNF-α inhibitor (IC50 = 13 nM). It also potently inhibits IL-2 (EC50 = 8 nM). It binds cereblon and inhibits its ubiquitination. Pomalidomide exhibits antiproliferative effects in a Namalwa lymphoma cell line and is antiangiogenic.
Info
| Purity | >95% |
| Quantity | 1 mg, 5 mg |
| Molecular Weight | 273.24 g/mol |
| Physical State | Lyophilized pale-yellow to yellow-brown solid |
| Solubility | 25 mg/mL in DMSO |
| CAS No. | 19171-19-8 |
| Storage | Room Temperature |
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