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PC1005: Pomalidomide

LifeSensors PC1005 is a specialized assay kit designed for ubiquitin pathway enzyme research, enabling precise analysis of ubiquitin ligases and deubiquitylases.

$55.00$225.00

SKU PC-1005 Categories ,

Pomalidomide is a cereblon ubiquitination inhibitor. It is also a TNF-α inhibitor and antiangiogenic.

Pomalidomide is a thalidomide derivative and a potent TNF-α inhibitor (IC50 = 13 nM). It also potently inhibits IL-2 (EC50 = 8 nM).  It binds cereblon and inhibits its ubiquitination. Pomalidomide exhibits antiproliferative effects in a Namalwa lymphoma cell line and is antiangiogenic.

Info

Purity  >95%
Quantity 1 mg, 5 mg
Molecular Weight 273.24 g/mol
Physical State Lyophilized pale-yellow to yellow-brown solid
Solubility 25 mg/mL in DMSO
CAS No. 19171-19-8
Storage Room Temperature

Pomalidomide is a cereblon ubiquitination inhibitor. It is also a TNF-α inhibitor and antiangiogenic.

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