Specifications
Mitophagy (the autophagic processing of damaged mitochondria) via Parkin activation is mainly promoted by K6 and K63 linked chains. K6-linked ubiquitination is also a main contributor to the DNA damage response and acts as a DNA-binding enhancer during the innate immune system response. These chain types are also involved in protein stabilization and other non-degradative processes. The serine in position 20 has been changed to a cysteine.
These tetra-ubiquitin chains are generated from the enzymatic linkage of wild-type ubiquitin through lysine 6.
Product Information
| Purity | ≥ 70% SDS-PAGE and Mass Spectrometry |
| Molecular Weight | 34267 Da |
| Physical State | Liquid |
| Quantity | 25 µg or 50 µg |
| Solubility | >30 mg/ml |
| Storage | -80°C, avoid freeze/thaw cycles |
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