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DB801: Den1, SENP8

LifeSensors DB801 is a lysine 48 poly-ubiquitin chain selective Tandem Ubiquitin Binding Entity (TUBE) for proteomics, enabling selective pull-down of poly-ubiquitylated proteins to enhance mass spec and drug discovery assays.

$138.00

In stock

Applications

  • This enzyme is active in the NEDD8-IsoPro assay.
DEN1 (SENP8, NEDP1) is a deNEDDylase. It deconjugates the NEDD8 moiety from NEDDylated proteins. A recent study demonstrated that DEN1 deNEDDylated the tumor suppressor breast cancer-associated protein BCA3. Also, full length DEN1 was shown to cleave NEDD8-PLA2 with high efficiency.

Info

Species Human
Source E. coli
Tag GST
Molecular Weight 51 kDa
Quantity 25 µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles
 

Applications

  • This enzyme is active in the NEDD8-IsoPro assay.

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