Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

DB505: USP14

LifeSensors DB505 is a specialized assay tool designed for precise ubiquitin-proteasome research, enabling advanced protein regulation and interaction studies

$152.00

In stock

In stock

USP14 (Ubiquitin Specific Protease 14) is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome-targeted ubiquitinated proteins. This enzyme serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded ER proteins via interaction with ERN1. It also plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.

Info

Species Human
Source E. coli
Tag His6 + SUMO
Molecular Weight 68 kDa
Quantity 25µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles

Applications

  • This enzyme cleaves K48-linked ubiquitin chains in vitro.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
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271 Great Valley Parkway Malvern, PA 19355

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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