DB302: AMSHcore

LifeSensors DB302 AMSHcore is a recombinant deubiquitylase protein (20.5 kDa) used in molecular biology, supplied in 25 µg quantities with a Tris-HCl buffer formulation.

$188.00

SKU DB-0302-0025 Categories DUBs, JAMM Family of DUBs Tags Deubiquitinating enzyme, DUB

In stock

Product Advantages

Applications

This enzyme cleaves K63-linked ubiquitin chains in vitro

AMSH (Associated Molecule with the SH3-domain of STAM, STAM Binding Protein) is a JAMM domain-containing protein that functions as a deubiquitinase in vitro. AMSHcore contains only the core domain of AMSH protein. AMSH mediates the cleavage of K63-linked ubiquitin chains. This cleavage is enhanced in the presence of its binding partner STAM. AMSH plays a role in the regulation of the endosomal sorting of the epidermal growth factor receptor (EGFR).

Info

Species	Human
Source	E. coli
Tag	His₆
Molecular Weight	20.5 kDa
Quantity	25 µg
Concentration	Variable
Formulation	50 mM Tris-HCl pH 8.0, 150 mM NaCl, 5 mM DTT, 10% glycerol
Storage	-80°C, avoid freeze/thaw cycles