Specifications
AMSH (Associated Molecule with the SH3-domain of STAM, STAM Binding Protein) is a JAMM domain-containing protein that functions as a deubiquitinase in vitro. AMSHcore contains only the core domain of AMSH protein. AMSH mediates the cleavage of K63-linked ubiquitin chains. This cleavage is enhanced in the presence of its binding partner STAM. AMSH plays a role in the regulation of the endosomal sorting of the epidermal growth factor receptor (EGFR).
Info
| Species | Human |
| Source | E. coli |
| Tag | His6 |
| Molecular Weight | 20.5 kDa |
| Quantity | 25 µg |
| Concentration | Variable |
| Formulation | 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 5 mM DTT, 10% glycerol |
| Storage | -80°C, avoid freeze/thaw cycles |
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