DB701-25µg SENP1core

DB401: Ataxin-3

$125.00

In stock

Specifications

Ataxin-3 (MJD1, SCA3) is a josephin domain-containing protein that functions as a deubiquitinase in vitro. It mediates the cleavage of long polyubiquitin chains while it has weak or no activity against chains of 4 or less ubiquitins. Ataxin-3 is the disease protein in spinocerebellar ataxia type 3 and plays a role in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates.

Info

Species Human
Source E. coli
Tag His6
Molecular Weight 41 kDa
Quantity 25 µg
Concentration Variable
Formulation  
Storage -80°C, avoid freeze/thaw cycles

Additional information

SKU

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Applications

  • This enzyme cleaves K48-linked ubiquitin chains in vitro

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