Specifications
Ataxin-3 (MJD1, SCA3) is a josephin domain-containing protein that functions as a deubiquitinase in vitro. It mediates the cleavage of long polyubiquitin chains while it has weak or no activity against chains of 4 or less ubiquitins. Ataxin-3 is the disease protein in spinocerebellar ataxia type 3 and plays a role in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates.
Info
| Species | Human |
| Source | E. coli |
| Tag | His6 |
| Molecular Weight | 41 kDa |
| Quantity | 25 µg |
| Concentration | Variable |
| Formulation | |
| Storage | -80°C, avoid freeze/thaw cycles |
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