Questions about a product, technology or experimental design? Give us a call 610-644-8845.

AC1005: LY-294002

LifeSensors AC1005 is a high-precision physiological pressure signal conditioner using fiber optic technology, ideal for accurate, real-time biomedical pressure monitoring.

$137.00 – $477.00

SKU AC-1005 Categories Autophagy Inhibitors, Autophagy Modulators, Small Molecule Modulators and PROTACs

Product Advantages

LY-294002 is a cell permeable highly selective inhibitor of phosphatidylinositol 3-kinase (IC50 = 0.31, 0.73, 1.06 and 6.60 µM for PI 3-Kβ, PI 3-Kα, PI 3-Kδ and PI 3-Kγ respectively). It inhibits autophagy in rat hepatocytes (IC50 = 10 µM). LY-294002 is an extremely useful tool for determining the role of PI 3-K in cellular signaling. It is more stable in solution than Wortmannin, and also blocks autophagosome formation.

Info

Purity	>98% by TLC
Quantity	5 mg, 25 mg
Molecular Weight	307.4 g/mol
Physical State	Lyophilized white powder
Solubility	20mg/mL in warm DMSO; 8 mg/mL in warm ethanol
CAS No.	154447-36-6
Storage	-20°C, avoid freeze/thaw cycles

Datasheet

Datasheet

send us a message for pricing

CONTACT INFORMATION

Phone (Office)

610.644.8845

SEND EMAIL

info@lifesensors.com

VISIT ANYTIME

271 Great Valley Parkway Malvern, PA 19355

More from This Category

SI9845: SKPin C1

LifeSensors SI9845 (SKPin C1) is a selective inhibitor of Skp2-mediated p27 degradation, inducing p27 accumulation and cell cycle arrest, used in cancer research and Skp2 studies.

AC1006: Pepstatin A

Lifesensors AC1006 (Pepstatin A) is a potent autophagy inhibitor used in research, available in 5mg and 25mg quantities for precise biochemical studies.

AC1002: 3-Methyladenine

LifeSensors AC1002 (3-Methyladenine) is a potent autophagy modulator widely used in research to inhibit autophagy pathways effectively

SI9639: LDN-57444, DUB inhibitor

LifeSensors SI9639 is a potent, selective inhibitor of USP7 deubiquitinase, used in research to study protein regulation and cancer therapy development.

PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.

Discovery

About lifesensors

Resources

Address: 271 Great Valley Parkway Malvern, PA 19355