Specifications
DBeQ is a cell-permeable, potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 μM. DBeQ blocks both ubiquitin-dependent and endoplasmic reticulum-associated degradation pathways, protein clearance pathways, and activates caspases -3 and -7 inducing apoptosis.
Info
| Purity | > 98% (TLC), NMR (Conforms) |
| Quantity | 10 mg, 25 mg |
| Molecular Weight | 340.4 Da |
| Physical State | Yellow powder |
| Solubility | DMSO (25mg/ml) |
| CAS No. | 177355-84-9 |
| Storage | 4°C, (-20°C Long term). The product can be shipped at room temperature. |
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