Specifications
A cell-permeable, non-peptide inhibitor of MDM2-p53 (HDM2-p53) interactions (Ki=120nM). Treatment of cancer cells activates p53 and accumulation of p21, p53, and MDM2 (HDM2). The structure mimics three p53 residues involved in binding to MDM2 (HDM2).
Info
Purity | >97% (TLC, HPLC), NMR (conforms) |
Quantity | 10 mg |
Molecular Weight | 340.4 Da |
Physical State | White solid |
Solubility | DMSO (25mg/ml) |
CAS No. | 6964-62-1 |
Storage | 4°C, (-20°C Long term). The product can be shipped at room temperature. |
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