UM420: Ubiquitin Mass Spectrometry Kit
The LifeSensors UM420 Ubiquitin Mass Spectrometry Kit is designed for comprehensive proteomic analysis of polyubiquitinated proteins, facilitating the identification of ubiquitination sites and the profiling of the ubiquitome. By integrating TUBE (Tandem Ubiquitin Binding Entities) technology with mass spectrometry, this kit enables the enrichment of ubiquitinated proteins from complex biological samples without the need for labeling. Applications include the discovery of novel E3 ligases and their substrates, mechanistic studies of ubiquitin signaling, and the evaluation of small-molecule drug candidates such as PROTACs and molecular glues. The UM420 kit is a valuable tool for advancing research in targeted protein degradation and biomarker discovery.
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