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Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UB303: Praja1

LifeSensors UB303 (Praja1) is an E3 ubiquitin ligase with a RING-H2 domain, involved in ubiquitin conjugation, essential for protein regulation and cellular processes research.

$529.00

In stock

In stock

Praja1 (along with Praja2, 53% identity) is a RING-H2 domain E3 (ubiquitin protein ligase) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E2 enzymes. Substrates for Praja1 include Dlxin-1 (MAGE-D1, human), which regulates Dlx5 dependent transcriptional function (involved in osteoblast differentiation), and ELF and Smad3, which are involved in the TGF-β signaling pathway implicated in gastrointestinal cancers.

Info

Species Human
Source E. coli
Tag His6-SUMO
Molecular Weight 71 kDa
Quantity 25 µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles

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