Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9639: LDN-57444, DUB inhibitor

LifeSensors SI9639 is a potent, selective inhibitor of USP7 deubiquitinase, used in research to study protein regulation and cancer therapy development.

Price range: $182.00 through $591.00

LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 µM) with approximately 28-fold greater selectivity over UCH-L3. Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.

Info

Purity > 98% (TLC); NMR (Conforms)
Quantity 10 mg, 50 mg
Molecular Weight 397.6 Da
Physical State Yellow powder
Solubility DMSO (20 mg/mL)
CAS No. 668467-91-2
Storage 4°C, (-20°C Long term). Store solutions at -20°C for up to one week. Protect from light. The product can be shipped at room temperature.
  • Inhibition of ubiquitin C-terminal hydrolase
  • Cell biology
  • Drug discovery
  • Benefits: cell-permeable

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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