SI0102-5µg (panel) Linear (Ub2) di-ubiquitin

SI3304: K33-Linked Tetra-Ubiquitin

LifeSensors SI3304 is a high-purity human K33-linked tetra-ubiquitin protein from E. coli, essential for studying ubiquitin signaling and protein regulation pathways.

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Product Advantages

• Investigation of phosphoubiquitin chain specificity and selectivity
• Studies on the role of phosphoubiquitin chains in protein degradation pathways (e.g., proteasomal and autophagic degradation)
• Analysis of phosphoubiquitin-mediated signaling pathways and cellular responses
• Structural studies to elucidate the architecture and dynamics of phosphoubiquitin chains
• Screening assays to identify modulators of phosphoubiquitin chain assembly and disassembly processes

K33-linked ubiquitination is traditionally associated with regulation of the innate immune response. These chain types are also involved in protein stabilization and other non-degradative processes. K33 Tetra-Ubiquitin is a tetrameric chain of wild-type ubiquitin, wherein ubiquitin monomers are enzymatically linked together via an isopeptide bond between Lysine 33 and the C-terminal Glycine. Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	34678 Da
Quantity	Variable
Concentration	Variable
Formulation	20 mM Tris pH 7.5, 150 mM NaCl
Storage	-80°C, avoid freeze/thaw cycles