Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UM312: TUBE 2 (HRP)

LifeSensors UM312 (TUBE 2 HRP) is a high-affinity polyubiquitin detection tool, enabling sensitive, selective pull-down and analysis of ubiquitylated proteins for proteomics and drug discovery.

$648.00

In stock

In stock

Based on protein domains known to possess an affinity for ubiquitin, Tandem Ubiquitin Binding Entities (TUBEs) have been developed for the isolation and identification of ubiquitylated proteins. TUBEs display up to a 1000-fold increase in affinity for polyubiquitin moieties over the single ubiquitin binding associated domain (UBA). In addition, TUBEs display a protective effect on polyubiquitinated proteins, allowing for detection at relatively low abundance. These properties effectively “capture” proteins in their polyubiquitylated state. We have developed the HRP-TUBE 2 for quick and easy detection of polyubiquitin and polyubiquitinated substrates. This product is protected by one or more US or Foreign patents. Please read the Limited Use Label License to learn more. By purchasing this product, the purchaser agrees to comply with these terms.

Info

Tag

HRP

Molecular Weight

56.5 kDa

Physical State

Liquid

Quantity

50 µg

Concentration

Variable

Storage

-80°C, avoid freeze/thaw cycles

Applications

  • Detection of polyubiquitylated proteins by ligand blotting (use a 1:1000 to 1:5000 dilution for most applications)
  • In situ labeling for detection of polyubiquitin by histochemistry

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

Visit Anytime

271 Great Valley Parkway Malvern, PA 19355

Send us a Message

Have a question about our solutions? We’d love to hear from you.
* Required fields

More from This Category

LifeSensors UM601 TUBE 1 (FLAG) offers up to 1000-fold higher affinity for isolating polyubiquitylated proteins, enhancing ubiquitin research without overexpressing....
LifeSensors UM604 (K63 TUBE FLAG) enables efficient isolation and enrichment of K63-polyubiquitinated proteins from cell and tissue extracts for advanced....
LifeSensors UM101 is a pan-ubiquitin antibody used for detecting ubiquitin and ubiquitinated proteins in research, supporting studies in protein degradation....
LifeSensors UM404M K63 TUBE Magnetic Beads enable specific enrichment of K63-linked polyubiquitin chains for studying ubiquitination in cell signaling and....

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Menu

Learning Center