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DB201: OTUB1

SKU DB-0201-0025 Categories , Tags ,
LifeSensors DB201 (OTUB1) is a K48-specific deubiquitinating enzyme that cleaves Lys48-linked polyubiquitin chains, essential for regulating protein degradation pathways

$182.00

In stock

In stock

OTUB1 (Otubain 1) is a member of the OTU (ovarian tumor) class of ubiquitin isopeptidases. It was originally identified as a protein capable of binding ubiquitin aldehyde. OTUB1 was shown to cleave K48-linked polyubiquitin chains in vitro. OTUB1 is involved in T cell function and is a substrate for Yersinia protein kinase.

Info

Species Human
Source E. coli
Tag His6
Molecular Weight 32 kDa
Quantity 25µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles

Applications

  • This enzyme cleaves K48- and K63-linked ubiquitin chains in vitro.

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