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Unraveling Chain specific Ubiquitination in Cells Using Tandem Ubiquitin Binding Entities in a High Throughput Assay
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LifeSensors Inc. Receives $5.53 Million Funds from National Institutes of Health to Develop PROTAC Drug Discovery and Diagnosis of Alzheimer’s Disease
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HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
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TUBEs work in Plants!
HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
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DUB
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SI270A: Ubiquitin, ALEXA-labeled
SI-270A-0025
Ubiquitin Chains and Derivatives
,
Ubiquitin Derivatives
Add to cart
SI401P: Phospho(Ser65)-Ubiquitin Mutant Biotinylated
SI-0401P
All
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Chains and Derivatives
Read more
SI0624: K6 Tetra-Ubiquitin (Ub4) Mutant
SI-0624
All
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Chains and Derivatives
Read more
K6 Tetra-Ubiquitin (Ub4) Wild-Type
SI-0614
All
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Chains and Derivatives
Read more
SI0623: K6 Tri-Ubiquitin (Ub3) Mutant
SI-0623
All
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Chains and Derivatives
Read more
UB402: Human PINK1
UB-0402-0025
Neurodegeneration Tools
,
PINK1 and Parkin Pathway Proteins
,
Ubiquitin and Neuro-degeneration
Read more
UB321: Parkin G284R Mutant E3 Ligase
UB-0321-0025
All
,
E3 Ubiquitin Ligases
,
Neurodegeneration Tools
,
PINK1 and Parkin Pathway Proteins
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Ligases and Enzymes
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UB320: Parkin R275W Mutant E3 Ligase
UB-0320-0025
All
,
E3 Ubiquitin Ligases
,
Neurodegeneration Tools
,
PINK1 and Parkin Pathway Proteins
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Ligases and Enzymes
Add to cart
UB319: Delta UBL Parkin E3 Ligase
UB-0319-0025
All
,
E3 Ubiquitin Ligases
,
Neurodegeneration Tools
,
PINK1 and Parkin Pathway Proteins
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Ligases and Enzymes
Add to cart
SI1102P: K11-Linked Di-Ubiquitin (Phosphorylated)
SI-1102P-0100
Neurodegeneration Tools
,
Phospho-Ubiquitin Chains and Derivatives
,
Phosphorylated Ubiquitin Chains
,
Phosphorylated Ubiquitin Chains
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Chains
,
Ubiquitin Chains and Derivatives
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In Vitro Assay in PROTAC
Ubiquitin Ligases and Enzymes
E1 Ubiquitin Activating Enzymes
E2 Ubiquitin Conjugating Enzymes
E3 Ubiquitin Ligases
Proteasomal Research Tools
Deubiquitinating Enzymes (DUBS)
USP Family of DUBs
UCH Family of DUBs
OTU Family of DUBs
JAMM Family of DUBs
MJD Family of DUBs
Viral and Bacterial DUBs
Deneddylases
DeSUMOylases
DUB Screening Assays
Antibodies
Kits and Plates
Colormetric Assays
E1-E2-E3 Assays
High-Throughput Plates
Target Protein Ubiquitination
Ubiquitination Assay
SUMO Protein Expression System
Bacteria
Mammalian Cells
Insect Cells
Yeast
Ubiquitin Chains and Derivatives
K to R Mutants
Ubiquitin Derivatives
Sumo Derivatives Chain
Isotropically-Labeled Ubiquitin
Small Molecule Modulators
Autophagy
E1-E2-E3 Inhibitors
DUB Inhibitors
Proteasome Inhibitors
P97 Inhibitors
Neurodegeneration Diagnostics and Research Tools
Phospho-Ubiquitin Antibodies
Phospho-Ubiquitin Chains and Derivatives
PINK1 and Parkin Pathway Proteins
Neuronal DUBs and Ligases
Phospho-Polyubiquitinated Enriched Lysates
TUBEs
Our Technologies
Tandem Ubiquitin Binding Entities (TUBEs)
E3 Ligase Assays
PROTAC Discovery Platform
Molecular Glue Discovery Platform
Mass Spec Proteomics
Imaging
Pulldown
Luciferase Reporters Applications for TPD
Reporters
PROTAC Applications
Molecular Glue Applications
Molecular Glue Degraders
Targeting E3 Ligase Applications
Substrate Targeting Applications
Ligase and Substrate Screening
PROTAC and DUBTAC Drug Discovery
LYTACs
BioPROTACs - MRNA Chimeras
Antibody Mediated Degradation
Exracellular Targeted Protein Degradation
Ubiquitin and Ubiquitin Chains
Ubiquitin Chains for DUB Screening
Biotinylated Ubiquitin Chains
Ubiquitin K to R mutants
SUMO Technology & Protein Expression
Polypeptide Manufacturing
Therapeutic Proteins, Dramatic Enhancement
Nanobodies and Single Chain Antibodies
Vaccine Manufacturing with SUMO
Gene Therapy: SUMO to the rescue
Neurodegeneration
Dysfunction of the Ubiquitin Proteasome System
Phospho-Ubiquitin as a Biomarker
Parkinsons Disease
Alzheimer’s Disease
Tandem Ubiquitin Binding Entities (TUBEs)
Molecular Glue Degraders
PROTAC and DUBTAC Drug Discovery
Ubiquitin and Ubiquitin Chains
SUMO Technology & Protein Expression
Neurodegeneration
Phospho-Ubiquitin as a Biomarker
Alzheimer’s Disease
R&D Services
PROTAC & Molecular Glues
PROTAC Degradation Assays
PROTAC Ubiquitination Assays
Target Exploration and Validation
Novel E3 Ligases For PROTAC
PROTAC Ternary Complex Formation Assays
PROTAC for Cancer
PROTAC for Neuroscience
SUMO-Fusion Protein Expression & Purification
Bacterial
SUMOpro E. Coli
SUMOstar
Advanced Therapeutic Applications
SUMOstar Mammalian
Ubiquitin E3 Ligase Assays, Drug Screening
Biochemical Assays
E3 Substrate Ubiquitination Assays
Gel-Based E3 Ligase Assay
Cell-Based E3 Substrate Assays
Novel E3 Ligases For PROTAC
Molecular Glue Degraders
In Vivo E3 Substrate Validation Assays
Thermal Shift Assay for E3 Ligases
Surface Plasmon Resonance for E3 Ligases
DUB Assays Screening & Profiling
Ubiquitin Flourophore Assays (Rhodamine, AMC, VME)
Ubiquitin Mass Spectrometry Proteomics
TUBE-Based Mass Spectrometry
E3 Ligase Substrate ID
DUB Substrate ID
Whole Cell Proteomics
Target Substrate ID
Ubiquitin Chain Diversity ID
Ligand Binding Assays
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Fluorescence Polarization
Custom Solutions
PROTAC & Molecular Glues
SUMO-Fusion Protein Expression & Purification
SUMOstar
Ubiquitin E3 Ligase Assays, Drug Screening
DUB Assays Screening & Profiling
Ubiquitin Mass Spectrometry Proteomics
Ligand Binding Assays
Custom Solutions
Resources
Learning Center
Ubiquitin Proteasome System
Therapeutic Relevance
Applications
FAQs
Protacs
TUBEs
SUMO
Learning Center
FAQs
Media
Press Releases
Unraveling Chain specific Ubiquitination in Cells Using Tandem Ubiquitin Binding Entities in a High Throughput Assay
Unveiling the Power of Molecular Glues at the 6th Annual Targeted Protein Degradation Summit
LifeSensors Inc. Receives $5.53 Million Funds from National Institutes of Health to Develop PROTAC Drug Discovery and Diagnosis of Alzheimer’s Disease
All Releases
Scientific Posters
HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
View More
Publications & Blogs
TUBEs work in Plants!
HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
Read More Blogs
Press Releases
Scientific Posters
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