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SI2702: K27-Linked Di-Ubiquitin

SKU SI-2702-0025 Categories ,
LifeSensors’ SI2702: K27-Linked Di-Ubiquitin protein is used for studying ubiquitination processes, crucial for regulating cellular functions and protein modification

$267.00

In stock

In stock

K27-Linked Di-Ubiquitin (Ub2) is a di-ubiquitin linked by a native isopeptide bond between the C-terminal glycine of the distal ubiquitin and the epsilon amino group of lysine 27 on the proximal ubiquitin. The product is generated using chemical ligation. It is a useful substrate for identifying and characterizing deubiquitinating enzymes that cleave the K27-linkage and for structural and binding studies of ubiquitin chain recognition by ubiquitin-associated domains (UBA) or ubiquitin-interacting motifs (UIMs).

Info

Species Human
Source E. coli
Tag None
Molecular Weight 17,112 Da
Quantity 25µg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 1 mM EDTA
Storage -80°C, avoid freeze/thaw cycles
  • Investigation of DUB linkage specificity

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