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Questions about a product, technology or experimental design? Give us a call 610-644-8845.

DB520: USP20

SKU DB-0520-0025 Categories , Tags ,
LifeSensors DB520 is a human recombinant USP20 enzyme (105 kDa, 25µg) active in deubiquitination assays, used for studying ubiquitin pathways and GPCR signaling regulation

$298.00

In stock

In stock

USP20 (Ubiquitin Specific Protease 20, VDU2) was identified by its homology to USP33 and binds competitively to the substrate recognition beta-domain of pVHL, a region commonly mutated in patients with pVHL disease. Furthermore, USP20 has been shown to be ubiquitinated by the pVHL E3 ligase complex in vitro and in cells. The enzyme acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2).

Info

Species Human
Source Insect
Tag His6
Molecular Weight 105 kDa
Quantity 25µg
Concentration Variable
Formulation 50 mM Tris pH 8.0, 150 mM NaCl, 1 mM EDTA, 5 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Applications

  • This enzyme is active in the Ub-CHOP assay.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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