Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UB229: UBE2L6

LifeSensors UB229 (UBE2L6) is an E2 ubiquitin-conjugating enzyme essential for ubiquitin attachment to target proteins, aiding studies in protein regulation and degradation.

Price range: $196.00 through $390.00

UBE2L6 (UbcH8) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. UBE2L6 is also the E2 utilized in the conjugation of the ubiquitin like protein (Ubl) ISG15 to its substrates (ISGylation) in concert with the ISG15 E1 (ISG15 activating enzyme). ISG15 is an interferon induced Ubl that is implicated in innate immunity pathways. UBE2L6 is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 17,768.8 Da
Quantity 0.8 nmol, 3.0 nmol
Concentration 40 µM
Formulation 50 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles
  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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