Questions about a product, technology or experimental design? Give us a call 610-644-8845. For special institutional pricing, check out our Distributors!
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9710: MG-132, proteasome inhibitor

LifeSensors SI9710 is a high-quality ubiquitin reagent designed for advanced research in protein degradation and signaling pathways, enhancing studies in ubiquitin biology.

Price range: $279.00 through $472.00

MG-132 is a potent, cell-permeable inhibitor of the proteasome (IC50=0.1 µM) and calpain (IC50=1.2 μM). MG-132 inhibits TNF-α-induced NF-κB activation and IκBα degradation (IC50=3 µM). MG-132 reduces the degradation of ubiquitin-conjugated proteins in different cell types and promotes apoptosis via activation of c-Jun N-terminal kinase (JNK1).

Info

Purity > 98% (HPLC)
Quantity 10 mg, 25 mg
Molecular Weight 475.6 Da
Physical State White powder
Solubility DMSO (45 mg/mL) or Ethanol (45 mg/mL)
CAS No. 133407-82-6
Storage 4°C, (-20°C Long term). Store solutions at -20°C for up to one week.  The product can be shipped at room temperature.
  • Inhibition of 20S proteasome chymotrypsin-like activity.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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