LifeSensors is pleased to bring attention to some of our academic colleagues who have used our products in the past to make discoveries and publications in the Ubiquitin Proteasome System field and further beyond. From E1s to SUMO expression, phosphorylation to deubiquitinases, we’re happy to have been a part of scientific discovery, and look forward to continue providing materials, services, and technical expertise to help build a strong scientific understanding, develop and further treatment of difficult to target diseases.

 

1: Diggin’ on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin
Ligase Substrates
Carrie E. Rubel, Jonathan C. Schisler, Eric D. Hamlett, Robert M. DeKroon, Mathias Gautel,
Oscar Alzate, Cam Patterson
Cell Biochem Biophys. Author manuscript; available in PMC 2014 September 1.Published in
final edited form as: Cell Biochem Biophys. 2013 September; 67(1): 127–138.
doi: 10.1007/s12013-013-9624-6
PMCID: PMC3758785

2: Recombinant Scorpine Produced Using SUMO Fusion Partner in Escherichia coli Has the
Activities against Clinically Isolated Bacteria and Inhibits the Plasmodium falciparum
Parasitemia In Vitro
Chao Zhang, Xinlong He, Yaping Gu, Huayun Zhou, Jun Cao, Qi Gao
PLoS One. 2014; 9(7): e103456. Published online 2014 July 28.
doi: 10.1371/journal.pone.0103456
PMCID: PMC4113386

3: The Aspartate-Less Receiver (ALR) Domains: Distribution, Structure and Function
Andrew F. Maule, David P. Wright, Joshua J. Weiner, Lanlan Han, Francis C. Peterson, Brian F.
Volkman, Nicholas R. Silvaggi, Andrew T. Ulijasz
PLoS Pathog. 2015 April; 11(4): e1004795. Published online 2015 April 13.
doi: 10.1371/journal.ppat.1004795Correction in: PLoS Pathog. 2015 June; 11(6): e1004951.
PMCID: PMC4395418

4: BLAP-Tags, TUBEs and DUB-Chips: Combined Novel Technologies will Advance
Molecular Epithelial Physiology
Kirk L. Hamilton
Front Physiol. 2012; 3: 137. Published online 2012 May 15. doi: 10.3389/fphys.2012.00137
PMCID: PMC3351676

5: A Comparative Analysis of the Ubiquitination Kinetics of Multiple Degrons to Identify an
Ideal Targeting Sequence for a Proteasome Reporter
Adam T. Melvin, Gregery S. Woss, Jessica H. Park, Lukas D. Dumberger, Marcey L. Waters,
Nancy L. AllbrittonPLoS One. 2013; 8(10): e78082. Published online 2013 October 29.
doi: 10.1371/journal.pone.0078082
PMCID: PMC3812159

6: The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for UbiquitinDependent Autophagy of Intracellular Salmonella Typhimurium
Alan Huett, Robert J. Heath, Jakob Begun, Slim O. Sassi, Leigh A. Baxt, Jatin M. Vyas, Marcia
B. Goldberg, Ramnik J. Xavier
Cell Host Microbe. Author manuscript; available in PMC 2013 December 13.Published in final
edited form as: Cell Host Microbe. 2012 December 13; 12(6): 778–790.
doi: 10.1016/j.chom.2012.10.019
PMCID: PMC3785244

7: Methods for Quantification of in vivo Changes in Protein Ubiquitination following
Proteasome and Deubiquitinase Inhibition
Namrata D. Udeshi, D. R. Mani, Thomas Eisenhaure, Philipp Mertins, Jacob D. Jaffe, Karl R.
Clauser, Nir Hacohen, Steven A. Carr
Mol Cell Proteomics. 2012 May; 11(5): 148–159. Published online 2012 April 14.
doi: 10.1074/mcp.M111.016857
PMCID: PMC3418844

8: MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase
DDX24
Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Kanae Yumimoto, Keiichi I.
Nakayama
Mol Cell Biol. 2014 September; 34(17): 3321–3340. doi: 10.1128/MCB.00320-14
PMCID: PMC4135551

9: Deubiquitylase, DeSUMOylase, and DeISGylase Activity Microarrays for Assay of Substrate
Preference and Functional Modifiers
Christian M. Loch, Charles L. Cuccherini, Craig A. Leach, James E. Strickler
Mol Cell Proteomics. 2011 January; 10(1): M110.002402. Published online 2010 October 18.
doi: 10.1074/mcp.M110.002402
PMCID: PMC3013450

10: Facilitated Tau Degradation by USP14 Aptamers via Enhanced Proteasome Activity
Jung Hoon Lee, Seung Kyun Shin, Yanxialei Jiang, Won Hoon Choi, Chaesun Hong, Dong-Eun
Kim, Min Jae Lee
Sci Rep. 2015; 5: 10757. Published online 2015 June 4. doi: 10.1038/srep10757
PMCID: PMC4455164

11: Role of ubiquitylation and USP8-dependent deubiquitylation in the endocytosis and
lysosomal targeting of plasma membrane KCa3.1
Corina M. Balut, Christian M. Loch, Daniel C. Devor
FASEB J. 2011 November; 25(11): 3938–3948. doi: 10.1096/fj.11-187005
PMCID: PMC3205838

12: Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by downregulating cholesterol synthesis and altering detergent resistant membranes composition
Giada Gelsomino, Paola A Corsetto, Ivana Campia, Gigliola Montorfano, Joanna Kopecka,
Barbara Castella, Elena Gazzano, Dario Ghigo, Angela M Rizzo, Chiara Riganti
Mol Cancer. 2013; 12: 137. Published online 2013 November 13. doi: 10.1186/1476-4598-12-
137
PMCID: PMC4225767

13: Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis
microRNA precursor processing
Yuji Iwata, Masateru Takahashi, Nina V. Fedoroff, Samir M. Hamdan
Nucleic Acids Res. 2013 October; 41(19): 9129–9140. Published online 2013 August 5.
doi: 10.1093/nar/gkt667
PMCID: PMC3799435

14: Factor Xa Activation of Factor V is of Paramount Importance in Initiating the Coagulation
System: Lessons from a Tick Salivary Protein
Tim J. Schuijt, Kamran Bakhtiari, Sirlei Daffre, Kathleen DePonte, Simone J.H. Wielders, J.
Arnoud Marquart, Joppe W. Hovius, Tom van der Poll, Erol Fikrig, Matthew W. Bunce, Rodney
M. Camire, Gerry A.F. Nicolaes, Joost C.M. Meijers, Cornelis van ‘t Veer
Circulation. Author manuscript; available in PMC 2014 July 16.Published in final edited form
as: Circulation. 2013 July 16; 128(3): 10.1161/CIRCULATIONAHA.113.003191. Published
online 2013 July 1. doi: 10.1161/CIRCULATIONAHA.113.003191
PMCID: PMC3826089

15: Structural and Functional Characterization of MppR, an Enduracididine Biosynthetic
Enzyme from Streptomyces hygroscopicus: Functional Diversity in the Acetoacetate
Decarboxylase-Like Superfamily
A. Maxwell Burroughs, Robert W. Hoppe, Neal C. Goebel, Bilal H. Sayyed, Tyler J. Voegtline,
Alan W. Schwabacher, T. Mark Zabriskie, Nicholas R. Silvaggi
Biochemistry. Author manuscript; available in PMC 2014 July 2.Published in final edited form
as: Biochemistry. 2013 July 2; 52(26): 4492–4506. Published online 2013 June 21.
doi: 10.1021/bi400397k
PMCID: PMC3743547

16: Chronic carvedilol treatment partially reverses the right ventricular failure transcriptional
profile in experimental pulmonary hypertension
Jennifer I. Drake, Jose Gomez-Arroyo, Catherine I. Dumur, Donatas Kraskauskas, Ramesh
Natarajan, Harm J. Bogaard, Paul Fawcett, Norbert F. Voelkel
Physiol Genomics. 2013 June 15; 45(12): 449–461. Published online 2013 April 30.
doi: 10.1152/physiolgenomics.00166.2012
PMCID: PMC3680777

17: A Co-Translational Ubiquitination Pathway For Quality Control of Misfolded Proteins
Feng Wang, Larissa A. Durfee, Jon M. Huibregtse
Mol Cell. Author manuscript; available in PMC 2014 May 9.Published in final edited form as:
Mol Cell. 2013 May 9; 50(3): 368–378. Published online 2013 April 11.
doi: 10.1016/j.molcel.2013.03.009
PMCID: PMC3654026

18: MreA Functions in the Global Regulation of Methanogenic Pathways in Methanosarcina
acetivorans

21: Identification of Targeting Peptides for Ischemic Myocardium by In Vivo Phage Display
Sachiko Kanki, Diana E. Jaalouk, Samuel Lee, Alvin Y.C. Yu, Joseph Gannon, Richard T. Lee
J Mol Cell Cardiol. Author manuscript; available in PMC 2012 May 1.Published in final edited
form as: J Mol Cell Cardiol. 2011 May; 50(5): 841–848. Published online 2011 February 24.
doi: 10.1016/j.yjmcc.2011.02.003
PMCID: PMC3075368

22: Inhibition of UCH-L1 in oligodendroglial cells results in microtubule stabilization and
prevents α-synuclein aggregate formation by activating the autophagic pathway: implications for
multiple system atrophy
Katharina Pukaß, Christiane Richter-Landsberg
Front Cell Neurosci. 2015; 9: 163. Published online 2015 May 5. doi: 10.3389/fncel.2015.00163
PMCID: PMC4419839

23: Identification of a Tsetse Fly Salivary Protein with Dual Inhibitory Action on Human
Platelet Aggregation
Guy Caljon, Karin De Ridder, Patrick De Baetselier, Marc Coosemans, Jan Van Den Abbeele
PLoS One. 2010; 5(3): e9671. Published online 2010 March 23.
doi: 10.1371/journal.pone.0009671
PMCID: PMC2843633

24: Biosimilars: the process is the product. The example of recombinant streptokinase
C Thelwell, C Longstaff
J Thromb Haemost. 2014 August; 12(8): 1229–1233. Published online 2014 July 31.
doi: 10.1111/jth.12629
PMCID: PMC4241032

25: Recombinant Antigens Expressed in Pichia pastoris for the Diagnosis of Sleeping Sickness
Caused by Trypanosoma brucei gambiense
Stijn Rogé, Liesbeth Van Nieuwenhove, Magali Meul, Annick Heykers, Annette Brouwer de
Koning, Nicolas Bebronne, Yves Guisez, Philippe Büscher
PLoS Negl Trop Dis. 2014 July; 8(7): e3006. Published online 2014 July 17.
doi: 10.1371/journal.pntd.0003006
PMCID: PMC4102443

26: Anterograde Trafficking of KCa3.1 in Polarized Epithelia Is Rab1- and Rab8-Dependent and
Recycling Endosome-Independent
Claudia A. Bertuccio, Shih-Liang Lee, Guangyu Wu, Michael B. Butterworth, Kirk L. Hamilton,
Daniel C. Devor PLoS One. 2014; 9(3): e92013. Published online 2014 March 14.
doi: 10.1371/journal.pone.0092013
PMCID: PMC3954861

27: MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP
degradation
K Shostak, F Patrascu, S I Göktuna, P Close, L Borgs, L Nguyen, F Olivier, A Rammal, H
Brinkhaus, M Bentires-Alj, J-C Marine, A Chariot
Cell Death Differ. 2014 May; 21(5): 811–824. Published online 2014 January 31.
doi: 10.1038/cdd.2014.2
PMCID: PMC3978309

28: Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein
CHIP
Chang-He Shi, Jonathan C. Schisler, Carrie E. Rubel, Song Tan, Bo Song, Holly McDonough,
Lei Xu, Andrea L. Portbury, Cheng-Yuan Mao, Cadence True, Rui-Hao Wang, Qing-Zhi Wang,
Shi-Lei Sun, Stephanie B. Seminara, Cam Patterson, Yu-Ming Xu
Hum Mol Genet. 2014 February 15; 23(4): 1013–1024. Published online 2013 October 9.
doi: 10.1093/hmg/ddt497
PMCID: PMC3900109

29: Restoring the Procofactor State of Factor Va-like Variants by Complementation with Bdomain Peptides
Matthew W. Bunce, Mettine H. A. Bos, Sriram Krishnaswamy, Rodney M. Camire
J Biol Chem. 2013 October 18; 288(42): 30151–30160. Published online 2013 September 6.
doi: 10.1074/jbc.M113.506840
PMCID: PMC3798483

30: To fuse or not to fuse: What is your purpose?
Mark R Bell, Mark J Engleka, Asim Malik, James E Strickler
Protein Sci. 2013 November; 22(11): 1466–1477. Published online 2013 August 26.
doi: 10.1002/pro.2356
PMCID: PMC3831663

31: S-nitrosylation regulates mitochondrial quality control via activation of parkin
Kentaro Ozawa, Akira T. Komatsubara, Yuhei Nishimura, Tomoyo Sawada, Hiroto Kawafune,
Hiroki Tsumoto, Yuichi Tsuji, Jing Zhao, Yoji Kyotani, Toshio Tanaka, Ryosuke Takahashi,
Masanori Yoshizumi
Sci Rep. 2013; 3: 2202. Published online 2013 July 16. doi: 10.1038/srep02202
PMCID: PMC3712319

32: Purification, crystallization and preliminary X-ray analysis of TP0435 (Tp17) from the
syphilis spirochete Treponema pallidum
Chad A. Brautigam, Ranjit K. Deka, Michael V. Norgard
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 April 1; 69(Pt 4): 453–455. Published
online 2013 March 28. doi: 10.1107/S1744309113006246
PMCID: PMC3614177

33: The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD
Pyrophosphatase with a Potential Role in Flavin Homeostasis
Ranjit K. Deka, Chad A. Brautigam, Wei Z. Liu, Diana R. Tomchick, Michael V. Norgard
J Biol Chem. 2013 April 19; 288(16): 11106–11121. Published online 2013 February 27.
doi: 10.1074/jbc.M113.449975
PMCID: PMC3630870

34: Solution Structure of Escherichia coli FeoA and Its Potential Role in Bacterial Ferrous Iron
Transport
Cheryl K. Y. Lau, Hiroaki Ishida, Zhihong Liu, Hans J. Vogel
J Bacteriol. 2013 January; 195(1): 46–55. doi: 10.1128/JB.01121-12
PMCID: PMC3536175

35: Enhanced protein expression in mammalian cells using engineered SUMO fusions: Secreted
phospholipase A2
Raymond J. Peroutka, Nabil Elshourbagy, Tara Piech, Tauseef R. Butt
Protein Sci. 2008 September; 17(9): 1586–1595. doi: 10.1110/ps.035576.108
PMCID: PMC2525526

36: Bioluminescence Assay Platform for Selective and Sensitive Detection of Ub/Ubl Proteases
Steven J. Orcutt, Jian Wu, Michael J. Eddins, Craig A. Leach, James E. Strickler
Biochim Biophys Acta. Author manuscript; available in PMC 2013 November 1.Published in
final edited form as: Biochim Biophys Acta. 2012 November; 1823(11): 2079–2086. Published
online 2012 June 15. doi: 10.1016/j.bbamcr.2012.06.004
PMCID: PMC3465522

37: Structural, bioinformatic, and in vivo analyses of two Treponema pallidum lipoproteins
reveal a unique TRAP transporter
Ranjit K. Deka, Chad A. Brautigam, Martin Goldberg, Peter Schuck, Diana R. Tomchick,
Michael V. Norgard
J Mol Biol. Author manuscript; available in PMC 2013 March 9.Published in final edited form
as: J Mol Biol. 2012 March 9; 416(5): 678–696. Published online 2012 January 27.
doi: 10.1016/j.jmb.2012.01.015
PMCID: PMC3289903

38: Characterization of Selective Ubiquitin and Ubiquitin-Like Protease Inhibitors Using a
Fluorescence-Based Multiplex Assay Format
Xufan Tian, Nigora S. Isamiddinova, Raymond J. Peroutka, Seth J. Goldenberg, Michael R.
Mattern, Benjamin Nicholson, Craig Leach
Assay Drug Dev Technol. 2011 April; 9(2): 165–173. doi: 10.1089/adt.2010.0317
PMCID: PMC3065724

39: Efficient and rapid protein expression and purification of small high disulfide containing
sweet protein brazzein in E. coli
Fariba Assadi-Porter, Sammy Patry, John L. Markley
Protein Expr Purif. Author manuscript; available in PMC 2009 April 1.Published in final edited
form as: Protein Expr Purif. 2008 April; 58(2): 263–268. Published online 2007 December 3.
doi: 10.1016/j.pep.2007.11.009
PMCID: PMC2374762

40: Evidence that Altered Cis Element Spacing Affects PpsR Mediated Redox Control of
Photosynthesis Gene Expression in Rubrivivax gelatinosus
Takayuki Shimizu, Zhuo Cheng, Katsumi Matsuura, Shinji Masuda, Carl E. Bauer
PLoS One. 2015; 10(6): e0128446. Published online 2015 June 1.
doi: 10.1371/journal.pone.0128446
PMCID: PMC4452267

41: Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell
lysates: application to screening of new anti-malarials
Lydia Mata-Cantero, Concepción Cid, Maria G Gomez-Lorenzo, Wendy Xolalpa, Fabienne
Aillet, J Julio Martín, Manuel S Rodriguez
Malar J. 2015; 14: 200. Published online 2015 May 14. doi: 10.1186/s12936-015-0708-1
PMCID: PMC4440562

42: A secretory kinase complex regulates extracellular protein phosphorylation
Jixin Cui, Junyu Xiao, Vincent S Tagliabracci, Jianzhong Wen, Meghdad Rahdar, Jack E Dixon
eLife. 2015; 4: e06120. Published online 2015 March 19. doi: 10.7554/eLife.06120Includes
additional comments & authors
PMCID: PMC4421793

43: Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol
domain and depends on unique sequence inserts
Matthew Hogg, Mineaki Seki, Richard D. Wood, Sylvie Doublié, Susan S. Wallace
J Mol Biol. Author manuscript; available in PMC 2012 January 21.Published in final edited form
as: J Mol Biol. 2011 January 21; 405(3): 642–652. Published online 2010 November 2.
doi: 10.1016/j.jmb.2010.10.041Correction in: volume 412 on page 316
PMCID: PMC3025778

44: HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit
of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation
Jinwoo Ahn, Thomas Vu, Zach Novince, Jennifer Guerrero-Santoro, Vesna Rapic-Otrin, Angela
M. Gronenborn
J Biol Chem. 2010 November 26; 285(48): 37333–37341. Published online 2010 September 24.
doi: 10.1074/jbc.M110.133181
PMCID: PMC2988339

45: A novel RNA molecular signature for activation of 2′-5′ oligoadenylate synthetase-1
Virginia K. Vachon, Brenda M. Calderon, Graeme L. Conn
Nucleic Acids Res. 2015 January 9; 43(1): 544–552. Published online 2014 December 4.
doi: 10.1093/nar/gku1289
PMCID: PMC4288181

46: Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension
Kousuke Kasahara, Yoshitaka Kawakami, Tohru Kiyono, Shigenobu Yonemura, Yoshifumi
Kawamura, Saho Era, Fumio Matsuzaki, Naoki Goshima, Masaki Inagaki
Nat Commun. 2014 October 1; 5: 5081. Published online 2014 October 1.
doi: 10.1038/ncomms6081
PMCID: PMC4205846

47: Solution Structure of the 2A Protease from a Common Cold Agent, Human Rhinovirus C2,
Strain W12
Woonghee Lee, Kelly E. Watters, Andrew T. Troupis, Nichole M. Reinen, Fabian P. Suchy,
Kylie L. Moyer, Ronnie O. Frederick, Marco Tonelli, David J. Aceti, Ann C. Palmenberg, John
L. Markley
PLoS One. 2014; 9(6): e97198. Published online 2014 June 17.
doi: 10.1371/journal.pone.0097198
PMCID: PMC4061012

48: Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging
Zachary T. Berndsen, Nicholas Keller, Shelley Grimes, Paul J. Jardine, Douglas E. Smith
Proc Natl Acad Sci U S A. 2014 June 10; 111(23): 8345–8350. Published online 2014 May 27.
doi: 10.1073/pnas.1405109111
PMCID: PMC4060647

49: Membrane protein stability can be compromised by detergent interactions with the
extramembranous soluble domains
Zhengrong Yang, Chi Wang, Qingxian Zhou, Jianli An, Ellen Hildebrandt, Luba A Aleksandrov,
John C Kappes, Lawrence J DeLucas, John R Riordan, Ina L Urbatsch, John F Hunt, Christie G
Brouillette
Protein Sci. 2014 June; 23(6): 769–789. Published online 2014 March 21. doi: 10.1002/pro.2460
PMCID: PMC4093953

50: Ubiquitin C-terminal Hydrolase L1 Interacts with Choline Transporter in Cholinergic Cells
Sigurd Hartnett, Fan Zhang, Allison Abitz, Yifan Li
Neurosci Lett. Author manuscript; available in PMC 2015 April 3.Published in final edited form
as: Neurosci Lett. 2014 April 3; 564: 115–119. Published online 2014 February 11.
doi: 10.1016/j.neulet.2014.02.007
PMCID: PMC4024205

51: Structural and Computational Studies of the Staphylococcus aureus Sortase B-Substrate
Complex Reveal a Substrate-stabilized Oxyanion Hole
Alex W. Jacobitz, Jeff Wereszczynski, Sung Wook Yi, Brendan R. Amer, Grace L. Huang,
Angelyn V. Nguyen, Michael R. Sawaya, Michael E. Jung, J. Andrew McCammon, Robert T.
Clubb
J Biol Chem. 2014 March 28; 289(13): 8891–8902. Published online 2014 February 11.
doi: 10.1074/jbc.M113.509273
PMCID: PMC3979406

52: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread
of kinase activity
Margaret Stratton, Il-Hyung Lee, Moitrayee Bhattacharyya, Sune M Christensen, Luke H Chao,
Howard Schulman, Jay T Groves, John Kuriyan
eLife. 2014; 3: e01610. Published online 2014 January 28. doi: 10.7554/eLife.01610Includes
additional comments & authorsCorrection in: eLife. 2014; 3: e02490.
PMCID: PMC3901001

53: Vitamin B12 regulates photosystem gene expression via the CrtJ antirepressor AerR in
Rhodobacter capsulatus
Zhuo Cheng, Keran Li, Loubna A. Hammad, Jonathan A. Karty, Carl E. Bauer
Mol Microbiol. Author manuscript; available in PMC 2015 February 1.Published in final edited
form as: Mol Microbiol. 2014 February; 91(4): 649–664. Published online 2014 January 9.
doi: 10.1111/mmi.12491
PMCID: PMC3946051

54: Differential Loss of Prolyl Isomerase or Chaperone Activity of Ran-binding Protein 2
(Ranbp2) Unveils Distinct Physiological Roles of Its Cyclophilin Domain in Proteostasis
Kyoung-in Cho, Hemangi Patil, Eugene Senda, Jessica Wang, Haiqing Yi, Sunny Qiu, Dosuk
Yoon, Minzhong Yu, Andrew Orry, Neal S. Peachey, Paulo A. Ferreira
J Biol Chem. 2014 February 21; 289(8): 4600–4625. Published online 2014 January 8.
doi: 10.1074/jbc.M113.538215
PMCID: PMC3931022

55: Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors
Targeting the ATP-binding Pocket
Shih-Chia Tso, Xiangbing Qi, Wen-Jun Gui, Cheng-Yang Wu, Jacinta L. Chuang, Ingrid
Wernstedt-Asterholm, Lorraine K. Morlock, Kyle R. Owens, Philipp E. Scherer, Noelle S.
Williams, Uttam K. Tambar, R. Max Wynn, David T. Chuang
J Biol Chem. 2014 February 14; 289(7): 4432–4443. Published online 2013 December 19.
doi: 10.1074/jbc.M113.533885
PMCID: PMC3924305

56: Haploid Genetic Screens Identify an Essential Role for PLP2 in the Downregulation of
Novel Plasma Membrane Targets by Viral E3 Ubiquitin Ligases
Richard T. Timms, Lidia M. Duncan, Iva A. Tchasovnikarova, Robin Antrobus, Duncan L.
Smith, Gordon Dougan, Michael P. Weekes, Paul J. Lehner
PLoS Pathog. 2013 November; 9(11): e1003772. Published online 2013 November 21.
doi: 10.1371/journal.ppat.1003772
PMCID: PMC3836740

57: Substrate Binding Promotes Formation of the Skp1-Cul1-Fbxl3 (SCFFbxl3) Protein
Complex
Kanae Yumimoto, Tetsuya Muneoka, Tomohiro Tsuboi, Keiichi I. Nakayama
J Biol Chem. 2013 November 8; 288(45): 32766–32776. Published online 2013 September 30.
doi: 10.1074/jbc.M113.511303
PMCID: PMC3820910

58: F-box and WD Repeat Domain-containing-7 (Fbxw7) Protein Targets Endoplasmic
Reticulum-anchored Osteogenic and Chondrogenic Transcriptional Factors for Degradation
Kanae Yumimoto, Masaki Matsumoto, Ichiro Onoyama, Kazunori Imaizumi, Keiichi I.
Nakayama
J Biol Chem. 2013 October 4; 288(40): 28488–28502. Published online 2013 August 16.
doi: 10.1074/jbc.M113.465179
PMCID: PMC3789950

59: Regulation of Stress-Inducible Phosphoprotein 1 Nuclear Retention by Protein Inhibitor of
Activated STAT PIAS1
Iaci N. Soares, Fabiana A. Caetano, Jordan Pinder, Bruna Roz Rodrigues, Flavio H. Beraldo,
Valeriy G. Ostapchenko, Chantal Durette, Grace Schenatto Pereira, Marilene H. Lopes, Nicolle
Queiroz-Hazarbassanov, Isabela W. Cunha, Paulo I. Sanematsu, Sergio Suzuki, Luiz F. BleggiTorres, Caroline Schild-Poulter, Pierre Thibault, Graham Dellaire, Vilma R. Martins, Vania F.
Prado, Marco A. M. Prado
Mol Cell Proteomics. 2013 November; 12(11): 3253–3270. Published online 2013 August 12.
doi: 10.1074/mcp.M113.031005
PMCID: PMC3820937

60: Human Mitochondrial Chaperone (mtHSP70) and Cysteine Desulfurase (NFS1) Bind
Preferentially to the Disordered Conformation, Whereas Co-chaperone (HSC20) Binds to the
Structured Conformation of the Iron-Sulfur Cluster Scaffold Protein (ISCU)
Kai Cai, Ronnie O. Frederick, Jin Hae Kim, Nichole M. Reinen, Marco Tonelli, John L. Markley
J Biol Chem. 2013 October 4; 288(40): 28755–28770. Published online 2013 August 12.
doi: 10.1074/jbc.M113.482042
PMCID: PMC3789972

61: Deubiquitinases Sharpen Substrate Discrimination during Membrane Protein Degradation
from the ER
Zai-Rong Zhang, Juan S. Bonifacino, Ramanujan S. Hegde
Cell. 2013 August 1; 154(3): 609–622. doi: 10.1016/j.cell.2013.06.038
PMCID: PMC3732389

62: OTULIN restricts Met1-linked ubiquitination to control innate immune signaling
Berthe Katrine Fiil, Rune Busk Damgaard, Sebastian Alexander Wagner, Kirstin Keusekotten,
Melanie Fritsch, Simon Bekker-Jensen, Niels Mailand, Chunaram Choudhary, David Komander,
Mads Gyrd-Hansen
Mol Cell. Author manuscript; available in PMC 2014 October 13.Published in final edited form
as: Mol Cell. 2013 June 27; 50(6): 818–830. doi: 10.1016/j.molcel.2013.06.004
PMCID: PMC4194427

63: Crystal structure of the Golgi casein kinase
Junyu Xiao, Vincent S. Tagliabracci, Jianzhong Wen, Soo-A Kim, Jack E. Dixon
Proc Natl Acad Sci U S A. 2013 June 25; 110(26): 10574–10579. Published online 2013 June
10. doi: 10.1073/pnas.1309211110
PMCID: PMC3696822

64: Mapping and Characterization of the Interaction Interface between Two PolypyrimidineTract Binding Proteins and a Nova-Type Protein of Solanum tuberosum
Shweta Shah, Nathaniel M. Butler, David J. Hannapel, A. Gururaj Rao
PLoS One. 2013; 8(5): e64783. Published online 2013 May 24.
doi: 10.1371/journal.pone.0064783
PMCID: PMC3663837

65: The Human CD8β M-4 Isoform Dominant in Effector Memory T Cells Has Distinct
Cytoplasmic Motifs That Confer Unique Properties
Deepshi Thakral, Maria M. Coman, Arunima Bandyopadhyay, Sunil Martin, James L. Riley,
Paula B. Kavathas
PLoS One. 2013; 8(3): e59374. Published online 2013 March 22.
doi: 10.1371/journal.pone.0059374
PMCID: PMC3606432

66: Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells
Jin-Gu Lee, Kheewoong Baek, Nia Soetandyo, Yihong Ye
Nat Commun. 2013 March 5; 4: 1568. Published online 2013 March 5.
doi: 10.1038/ncomms2532
PMCID: PMC3615374

67: Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes
Ranjit K. Deka, Chad A. Brautigam, Brent A. Biddy, Wei Z. Liu, Michael V. Norgard
mBio. 2013 Jan-Feb; 4(1): e00615-12. Published online 2013 February 12.
doi: 10.1128/mBio.00615-12
PMCID: PMC3573665

68: Proteasome inhibition prolongs survival during lethal hemorrhagic shock in rats
Harold H. Bach, IV, Heather M. LaPorte, Yee M. Wong, Richard L. Gamelli, Matthias
Majetschak
J Trauma Acute Care Surg. Author manuscript; available in PMC 2014 October 2.Published in
final edited form as: J Trauma Acute Care Surg. 2013 February; 74(2): 499–507.
doi: 10.1097/TA.0b013e31827d5db2
PMCID: PMC4182954

69: Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables
Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments
Namrata D. Udeshi, Tanya Svinkina, Philipp Mertins, Eric Kuhn, D. R. Mani, Jana W. Qiao,
Steven A. Carr
Mol Cell Proteomics. 2013 March; 12(3): 825–831. Published online 2012 December 24.
doi: 10.1074/mcp.O112.027094
PMCID: PMC3591673

70: Transient kinetic analysis of USP2-catalyzed deubiquitination reveals a conformational
rearrangement in the K48-linked diubiquitin substrate
William P. Bozza, Qin Liang, Ping Gong, Zhihao Zhuang
Biochemistry. Author manuscript; available in PMC 2013 December 18.Published in final edited
form as: Biochemistry. 2012 December 18; 51(50): 10075–10086. Published online 2012
December 4. doi: 10.1021/bi3009104
PMCID: PMC3617563

71: Nonenzymatic Polymerization of Ubiquitin: Single-Step Synthesis and Isolation of Discrete
Ubiquitin Oligomers
Vivian H. Trang, Ellen M. Valkevich, Shoko Minami, Yi-Chen Chen, Ying Ge, Eric R. Strieter
Angew Chem Int Ed Engl. Author manuscript; available in PMC 2014 July 7.Published in final
edited form as: Angew Chem Int Ed Engl. 2012 December 21; 51(52): 13085–13088. Published
online 2012 November 19. doi: 10.1002/anie.201207171
PMCID: PMC4083817

72: Involvement of WalK (VicK) Phosphatase Activity in Setting WalR (VicR) Response
Regulator Phosphorylation Level and Limiting Crosstalk in Streptococcus pneumoniae D39
Cells
Kyle J. Wayne, Shuo Li, Krystyna M. Kazmierczak, Ho-Ching T. Tsui, Malcolm E. Winkler
Mol Microbiol. Author manuscript; available in PMC 2013 November 1.Published in final edited
form as: Mol Microbiol. 2012 November; 86(3): 645–660. Published online 2012 September 27.
doi: 10.1111/mmi.12006
PMCID: PMC3638944

73: TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome
maturation
Manohar Pilli, John Arko-Mensah, Marisa Ponpuak, Esteban Roberts, Sharon Master, Michael
Mandell, Nicolas Dupont, Wojciech Ornatowski, Shanya Jiang, Steven Bradfute, Jack-Ansgar
Bruun, Tom Egil Hansen, Terje Johansen, Vojo Deretic
Immunity. Author manuscript; available in PMC 2013 August 24.Published in final edited form
as: Immunity. 2012 August 24; 37(2): 223–234. doi: 10.1016/j.immuni.2012.04.015
PMCID: PMC3428731

74: PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli
Damien Garbett, Anthony Bretscher
J Cell Biol. 2012 July 23; 198(2): 195–203. doi: 10.1083/jcb.201204008
PMCID: PMC3410424

75: The tyrosine phosphatase STEP: implications in schizophrenia and the molecular
mechanism underlying antipsychotic medications
N C Carty, J Xu, P Kurup, J Brouillette, S M Goebel-Goody, D R Austin, P Yuan, G Chen, P R
Correa, V Haroutunian, C Pittenger, P J Lombroso
Transl Psychiatry. 2012 July; 2(7): e137. Published online 2012 July 10.
doi: 10.1038/tp.2012.63
PMCID: PMC3410627

76: Molecular Basis of Lys-63-linked Polyubiquitination Inhibition by the Interaction between
Human Deubiquitinating Enzyme OTUB1 and Ubiquitin-conjugating Enzyme UBC13
Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Keiko Kubota, Rikako Miyamoto,
Shinichiro Nakada, Shuya Fukai
J Biol Chem. 2012 July 27; 287(31): 25860–25868. Published online 2012 June 7.
doi: 10.1074/jbc.M112.364752
PMCID: PMC3406671

77: Characterization of a Glucosyltransferase Enzyme Involved in the Formation of Kaempferol
and Quercetin Sophorosides in Crocus sativus
Almudena Trapero, Oussama Ahrazem, Angela Rubio-Moraga, Maria Luisa Jimeno, Maria
Dolores Gómez, Lourdes Gómez-Gómez
Plant Physiol. 2012 August; 159(4): 1335–1354. Published online 2012 May 30.
doi: 10.1104/pp.112.198069
PMCID: PMC3425182

78: Monoubiquitination Promotes Calpain Cleavage of the Protein Phosphatase 2A (PP2A)
Regulatory Subunit α4, Altering PP2A Stability and Microtubule-associated Protein
Phosphorylation
Guy R. Watkins, Ning Wang, Matthew D. Mazalouskas, Rey J. Gomez, Chris R. Guthrie, Brian
C. Kraemer, Susann Schweiger, Benjamin W. Spiller, Brian E. Wadzinski
J Biol Chem. 2012 July 13; 287(29): 24207–24215. Published online 2012 May 21.
doi: 10.1074/jbc.M112.368613
PMCID: PMC3397847

79: Role of Ubiquitin in Parainfluenza Virus 5 Particle Formation
Megan S. Harrison, Phuong Tieu Schmitt, Zifei Pei, Anthony P. Schmitt
J Virol. 2012 April; 86(7): 3474–3485. doi: 10.1128/JVI.06021-11
PMCID: PMC3302527

80: Toward Low-Cost Affinity Reagents: Lyophilized Yeast-scFv Probes Specific for Pathogen
Antigens
Sean A. Gray, Kris M. Weigel, Ibne K. M. Ali, Annie A. Lakey, Jeremy Capalungan, Gonzalo J.
Domingo, Gerard A. Cangelosi
PLoS One. 2012; 7(2): e32042. Published online 2012 February 20.
doi: 10.1371/journal.pone.0032042
PMCID: PMC3282784

81: Selectivity in Post-translational Biotin Addition to Five Human Carboxylases
Maria Ingaramo, Dorothy Beckett
J Biol Chem. 2012 January 13; 287(3): 1813–1822. Published online 2011 November 28.
doi: 10.1074/jbc.M111.275982
PMCID: PMC3265863

82: A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulindependent kinase II holoenzyme
Luke H. Chao, Margaret M. Stratton, Il-Hyung Lee, Oren S. Rosenberg, Joshua Levitz, Daniel J.
Mandell, Tanja Kortemme, Jay T. Groves, Howard Schulman, John Kuriyan
Cell. Author manuscript; available in PMC 2012 March 2.Published in final edited form as: Cell.
2011 September 2; 146(5): 732–745. doi: 10.1016/j.cell.2011.07.038Correction in: volume 147
on page 704
PMCID: PMC3184253

83: Eliminating SF-1 (NR5A1) Sumoylation In Vivo Results in Ectopic Hedgehog Signaling
and Disruption of Endocrine Development
Florence Y. Lee, Emily J. Faivre, Miyuki Suzawa, Erik Lontok, Daniel Ebert, Fang Cai, Denise
D. Belsham, Holly A. Ingraham
Dev Cell. Author manuscript; available in PMC 2012 August 16.Published in final edited form
as: Dev Cell. 2011 August 16; 21(2): 315–327. Published online 2011 August 4.
doi: 10.1016/j.devcel.2011.06.028
PMCID: PMC3157481

84: Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylatebinding Protein 2 (GBP2) by Modulating Macroautophagy
Maria K. Traver, Stanley C. Henry, Viviana Cantillana, Tim Oliver, Julia P. Hunn, Jonathan C.
Howard, Sandra Beer, Klaus Pfeffer, Jörn Coers, Gregory A. Taylor
J Biol Chem. 2011 September 2; 286(35): 30471–30480. Published online 2011 July 12.
doi: 10.1074/jbc.M111.251967Correction in: J Biol Chem. 2013 April 19; 288(16): 11504.
PMCID: PMC3162407

85: The variable detergent sensitivity of proteases that are utilized for recombinant protein
affinity tag removal
James M. Vergis, Michael C. Wiener
Protein Expr Purif. Author manuscript; available in PMC 2012 August 1.Published in final
edited form as: Protein Expr Purif. 2011 August; 78(2): 139–142. Published online 2011 April
24. doi: 10.1016/j.pep.2011.04.011
PMCID: PMC3130611

86: The E3 Ubiquitin Ligase- and Protein Phosphatase 2A (PP2A)-binding Domains of the
Alpha4 Protein Are Both Required for Alpha4 to Inhibit PP2A Degradation
Michele LeNoue-Newton, Guy R. Watkins, Ping Zou, Katherine L. Germane, Lisa R.
McCorvey, Brian E. Wadzinski, Benjamin W. Spiller
J Biol Chem. 2011 May 20; 286(20): 17665–17671. Published online 2011 March 29.
doi: 10.1074/jbc.M111.222414
PMCID: PMC3093842

87: Biotinylation, a Post-translational Modification Controlled by the Rate of Protein-Protein
Association
Maria Ingaramo, Dorothy Beckett
J Biol Chem. 2011 April 15; 286(15): 13071–13078. Published online 2011 February 22.
doi: 10.1074/jbc.M110.183624
PMCID: PMC3075653

88: Challenges associated with the targeted delivery of gelonin to claudin-expressing cancer
cells with the use of activatable cell penetrating peptides to enhance potency
Xiaoqin Yuan, Xinjian Lin, Gerald Manorek, Stephen B Howell
BMC Cancer. 2011; 11: 61. Published online 2011 February 8. doi: 10.1186/1471-2407-11-61
PMCID: PMC3042419

89: SUMOylation of DLX3 by SUMO1 promotes its transcriptional activity
O. Duverger, S.X. Chen, D. Lee, T. Li, P.B. Chock, M.I. Morasso
J Cell Biochem. Author manuscript; available in PMC 2012 February 1.Published in final edited
form as: J Cell Biochem. 2011 February; 112(2): 445–452. doi: 10.1002/jcb.22891
PMCID: PMC3180851

90: A Quantitative Model of Thermal Stabilization and Destabilization of Proteins by Ligands
Piotras Cimmperman, Lina Baranauskienė, Simona Jachimovičiūtė, Jelena Jachno, Jolanta
Torresan, Vilma Michailovienė, Jurgita Matulienė, Jolanta Sereikaitė, Vladas Bumelis,
Daumantas Matulis
Biophys J. 2008 October 1; 95(7): 3222–3231. Published online 2008 July 3.
doi: 10.1529/biophysj.108.134973
PMCID: PMC2547457

91: Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities
Benjamin Nicholson, Craig A. Leach, Seth J. Goldenberg, Dana M. Francis, Matthew P.
Kodrasov, Xufan Tian, John Shanks, David E. Sterner, Alejandro Bernal, Michael R. Mattern,
Keith D. Wilkinson, Tauseef R. Butt
Protein Sci. 2008 June; 17(6): 1035–1043. doi: 10.1110/ps.083450408
PMCID: PMC2386736

92: SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis
Luyang Yu, Weidong Ji, Haifeng Zhang, Matthew J. Renda, Yun He, Sharon Lin, Ee-chun
Cheng, Hong Chen, Diane S. Krause, Wang Min
J Exp Med. 2010 June 7; 207(6): 1183–1195. doi: 10.1084/jem.20092215
PMCID: PMC2882842

93: Crystallization and preliminary crystallographic studies of the catalytic subunits of human
pyruvate dehydrogenase phosphatase isoforms 1 and 2
Junko Kato, Masato Kato
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 March 1; 66(Pt 3): 342–345.
Published online 2010 February 27. doi: 10.1107/S1744309110003131
PMCID: PMC2833053

94: Kinetic Characterization of the WalRKSpn (VicRK) Two-Component System of
Streptococcus pneumoniae: Dependence of WalKSpn (VicK) Phosphatase Activity on Its PAS
Domain
Alina D. Gutu, Kyle J. Wayne, Lok-To Sham, Malcolm E. Winkler
J Bacteriol. 2010 May; 192(9): 2346–2358. Published online 2010 February 26.
doi: 10.1128/JB.01690-09
PMCID: PMC2863487

95: Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen
Receptor
X. Edward Zhou, Kelly M. Suino-Powell, Jun Li, Yuanzheng He, Jeffrey P. MacKeigan, Karsten
Melcher, Eu-Leong Yong, H. Eric Xu
J Biol Chem. 2010 March 19; 285(12): 9161–9171. Published online 2010 January 19.
doi: 10.1074/jbc.M109.085779
PMCID: PMC2838335

96: Cerebrospinal Fluid Secretory Ca2+-Dependent Phospholipase A2 Activity Is Increased in
Alzheimer Disease
Sonia Chalbot, Henrik Zetterberg, Kaj Blennow, Tormod Fladby, Inge Grundke-Iqbal, Khalid
Iqbal
Clin Chem. Author manuscript; available in PMC 2010 April 21.Published in final edited form
as: Clin Chem. 2009 December; 55(12): 2171–2179. Published online 2009 October 22.
doi: 10.1373/clinchem.2009.130286
PMCID: PMC2857971

97: The molecular basis for the regulation of the CBC by the importins
Sandra M.G. Dias, Kristin F. Wilson, Katherine S. Rojas, Andre L.B. Ambrosio, Richard A.
Cerione
Nat Struct Mol Biol. Author manuscript; available in PMC 2010 March 1.Published in final
edited form as: Nat Struct Mol Biol. 2009 September; 16(9): 930–937. Published online 2009
August 9. doi: 10.1038/nsmb.1649
PMCID: PMC2782468

98: Molecular Identification and Expression Analysis of Filaggrin-2, a Member of the S100
Fused-Type Protein Family
Zhihong Wu, Britta Hansmann, Ulf Meyer-Hoffert, Regine Gläser, Jens-Michael Schröder
PLoS ONE. 2009; 4(4): e5227. Published online 2009 April 22.
doi: 10.1371/journal.pone.0005227
PMCID: PMC2668185

99: Identification of Lympho-Epithelial Kazal-Type Inhibitor 2 in Human Skin as a KallikreinRelated Peptidase 5-Specific Protease Inhibitor
Ulf Meyer-Hoffert, Zhihong Wu, Jens-Michael Schröder
PLoS ONE. 2009; 4(2): e4372. Published online 2009 February 3.
doi: 10.1371/journal.pone.0004372
PMCID: PMC2631147

100: The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
Jonathan A Winger, Emily R Derbyshire, Meindert H Lamers, Michael A Marletta, John
Kuriyan
BMC Struct Biol. 2008; 8: 42. Published online 2008 October 7. doi: 10.1186/1472-6807-8-42
PMCID: PMC2576301

101: Decreased Recognition of SUMO-Sensitive Target Genes following Modification of SF-1
(NR5A1)
Lioudmila A. Campbell, Emily J. Faivre, Matthew D. Show, Jared G. Ingraham, Jeremy
Flinders, John D. Gross, Holly A. Ingraham
Mol Cell Biol. 2008 December; 28(24): 7476–7486. Published online 2008 October 6.
doi: 10.1128/MCB.00103-08
PMCID: PMC2593425

102: Enhanced protein expression in the baculovirus/insect cell system using engineered SUMO
fusions
Li Liu, Joshua Spurrier, Tauseef R. Butt, James E. Strickler
Protein Expr Purif. Author manuscript; available in PMC 2009 November 1.Published in final
edited form as: Protein Expr Purif. 2008 November; 62(1): 21–28. Published online 2008 August
5. doi: 10.1016/j.pep.2008.07.010
PMCID: PMC2585507

103: Nucleotidylylation of the VPg Protein of a Human Norovirus by its Proteinase-Polymerase
Precursor Protein
Gaël Belliot, Stanislav V. Sosnovtsev, Kyeong-Ok Chang, Peter McPhie, Kim Y. Green
Virology. Author manuscript; available in PMC 2009 April 25.Published in final edited form as:
Virology. 2008 April 25; 374(1): 33–49. Published online 2008 January 30.
doi: 10.1016/j.virol.2007.12.028
PMCID: PMC2386983

104: Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion
transport
Sreekanth Rajan, Minjoo Choi, Quoc Toan Nguyen, Hong Ye, Wei Liu, Hui Ting Toh, CongBao
Kang, Neelagandan Kamariah, Chi Li, Huiya Huang, Carl White, Kwanghee Baek, Gerhard
Grüber, Ho Sup Yoon
Sci Rep. 2015; 5: 10609. Published online 2015 May 29. doi: 10.1038/srep10609
PMCID: PMC4448555

105: K63 linked ubiquitin chain formation is a signal for HIF1A degradation by ChaperoneMediated Autophagy
Joao Vasco Ferreira, Ana Rosa Soares, Jose Silva Ramalho, Paulo Pereira, Henrique Girao
Sci Rep. 2015; 5: 10210. Published online 2015 May 11. doi: 10.1038/srep10210
PMCID: PMC4426689

106: Oligomerization of FtsZ converts the FtsZ tail motif (CCTP) into a multivalent ligand with
high avidity for partners ZipA and SlmA
Shishen Du, Kyung-Tae Park, Joe Lutkenhaus
Mol Microbiol. Author manuscript; available in PMC 2015 March 18.Published in final edited
form as: Mol Microbiol. 2015 January; 95(2): 173–188. Published online 2014 December 19.
doi: 10.1111/mmi.12854
PMCID: PMC4364296

107: Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3
from the Middle East Respiratory Syndrome Coronavirus
Yahira M. Báez-Santos, Anna M. Mielech, Xufang Deng, Susan Baker, Andrew D. Mesecar
J Virol. 2014 November; 88(21): 12511–12527. doi: 10.1128/JVI.01294-14
PMCID: PMC4248884

108: Recruitment of Cbl-b to B Cell Antigen Receptor Couples Antigen Recognition to TollLike Receptor 9 Activation in Late Endosomes
Margaret Veselits, Azusa Tanaka, Stanley Lipkowitz, Shannon O’Neill, Roger Sciammas, Alison
Finnegan, Jian Zhang, Marcus R. Clark
PLoS One. 2014; 9(3): e89792. Published online 2014 March 20.
doi: 10.1371/journal.pone.0089792
PMCID: PMC3961229

109: 19F NMR Reveals Multiple Conformations at the Dimer Interface of the Non-Structural
Protein 1 Effector Domain from Influenza A Virus
James M. Aramini, Keith Hamilton, Li-Chung Ma, G. V. T. Swapna, Paul G. Leonard, John E.
Ladbury, Robert M. Krug, Gaetano T. Montelione
Structure. Author manuscript; available in PMC 2015 April 8.Published in final edited form as:
Structure. 2014 April 8; 22(4): 515–525. Published online 2014 February 27.
doi: 10.1016/j.str.2014.01.010
PMCID: PMC4110948

110: Induction of Gsk3β-β-TrCP Interaction Is Required for Late Phase Stabilization of βCatenin in Canonical Wnt Signaling
Chenxi Gao, Guangming Chen, Guillermo Romero, Stergios Moschos, Xiang Xu, Jing Hu
J Biol Chem. 2014 March 7; 289(10): 7099–7108. Published online 2014 January 22.
doi: 10.1074/jbc.M113.532606
PMCID: PMC3945370

111: Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited
conformational defect at the plasma membrane
Pirjo M. Apaja, Brian Foo, Tsukasa Okiyoneda, William C. Valinsky, Herve Barriere, Roxana
Atanasiu, Eckhard Ficker, Gergely L. Lukacs, Alvin Shrier
Mol Biol Cell. 2013 December 15; 24(24): 3787–3804. doi: 10.1091/mbc.E13-07-0417
PMCID: PMC3861077

112: The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and
dynamics
Damien Garbett, Cécile Sauvanet, Raghuvir Viswanatha, Anthony Bretscher
Mol Biol Cell. 2013 November 1; 24(21): 3381–3392. doi: 10.1091/mbc.E13-06-0330
PMCID: PMC3814156

113: Error rates for nanopore discrimination among cytosine, methylcytosine, and
hydroxymethylcytosine along individual DNA strands
Jacob Schreiber, Zachary L. Wescoe, Robin Abu-Shumays, John T. Vivian, Baldandorj Baatar,
Kevin Karplus, Mark Akeson
Proc Natl Acad Sci U S A. 2013 November 19; 110(47): 18910–18915. Published online 2013
October 28. doi: 10.1073/pnas.1310615110
PMCID: PMC3839712

114: Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human
cGAS
Kazuki Kato, Ryohei Ishii, Eiji Goto, Ryuichiro Ishitani, Fuminori Tokunaga, Osamu Nureki
PLoS One. 2013; 8(10): e76983. Published online 2013 October 7.
doi: 10.1371/journal.pone.0076983
PMCID: PMC3792152

115: Antimicrobial Activity of High-Mobility-Group Box 2: a New Function to a Well-Known
Protein
Robert Küchler, Bjoern O. Schroeder, Simon U. Jaeger, Eduard F. Stange, Jan Wehkamp
Antimicrob Agents Chemother. 2013 October; 57(10): 4782–4793. doi: 10.1128/AAC.00805-13
PMCID: PMC3811396

116: Using Antiubiquitin Antibodies to Probe the Ubiquitination State Within rhTRIM5α
Cytoplasmic Bodies
Cindy M. Danielson, Thomas J. Hope
AIDS Res Hum Retroviruses. 2013 October; 29(10): 1373–1385. doi: 10.1089/aid.2013.0029
PMCID: PMC3785812

117: Jun Activation Domain-binding Protein 1 (JAB1) Is Required for the Optimal Response to
Interferons
Ryuta Muromoto, Maiko Nakajima, Koki Hirashima, Toru Hirao, Shigeyuki Kon, Kazuya
Shimoda, Kenji Oritani, Tadashi Matsuda
J Biol Chem. 2013 October 25; 288(43): 30969–30979. Published online 2013 September 16.
doi: 10.1074/jbc.M113.485847
PMCID: PMC3829410

118: SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria
Hitoshi Murata, Masakiyo Sakaguchi, Ken Kataoka, Nam-ho Huh
Mol Biol Cell. 2013 September 15; 24(18): 2772–2784. doi: 10.1091/mbc.E13-01-0016
PMCID: PMC3771941

119: Measuring activity in the ubiquitin-proteasome system: From large scale discoveries to
single cells analysis
Adam T. Melvin, Gregery S. Woss, Jessica H. Park, Marcey L. Waters, Nancy L. Allbritton
Cell Biochem Biophys. Author manuscript; available in PMC 2014 September 1.Published in
final edited form as: Cell Biochem Biophys. 2013 September; 67(1): 75–89.
doi: 10.1007/s12013-013-9621-9
PMCID: PMC3758771

120: Redox and Light Control the Heme-Sensing Activity of AppA
Liang Yin, Vladimira Dragnea, George Feldman, Loubna A. Hammad, Jonathan A. Karty,
Charles E. Dann, III, Carl E. Bauer
mBio. 2013 Sep-Oct; 4(5): e00563-13. Published online 2013 August 27.
doi: 10.1128/mBio.00563-13
PMCID: PMC3760249

121: Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases
Treg-Cell-Suppressive Capacity
Jorg van Loosdregt, Veerle Fleskens, Juan Fu, Arjan B. Brenkman, Cornelis P.J. Bekker,
Cornelieke E.G.M. Pals, Jenny Meerding, Celia R. Berkers, Joseph Barbi, Andrea Gröne, Alice
J.A.M. Sijts, Madelon M. Maurice, Eric Kalkhoven, Berent J. Prakken, Huib Ovaa, Fan Pan,
Dietmar M.W. Zaiss, Paul J. Coffer
Immunity. Author manuscript; available in PMC 2014 August 15.Published in final edited form
as: Immunity. 2013 August 22; 39(2): 259–271. doi: 10.1016/j.immuni.2013.05.018
PMCID: PMC4133784

122: E2 ubiquitin conjugating enzymes regulate the deubiquitinating activity of OTUB1
Reuven Wiener, Anthony T. DiBello, Patrick Lombardi, Catherine M. Guzzo, Xiangbin Zhang,
Michael J. Matunis, Cynthia Wolberger
Nat Struct Mol Biol. Author manuscript; available in PMC 2014 March 4.Published in final
edited form as: Nat Struct Mol Biol. 2013 September; 20(9): 1033–1039. Published online 2013
August 18. doi: 10.1038/nsmb.2655
PMCID: PMC3941643

123: Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes
Mads Daugaard, Roberto Nitsch, Babak Razaghi, Lindsay McDonald, Ameer Jarrar, Stéphanie
Torrino, Sonia Castillo-Lluva, Barak Rotblat, Liheng Li, Angeliki Malliri, Emmanuel Lemichez,
Amel Mettouchi, Jason N. Berman, Josef M. Penninger, Poul H. Sorensen
Nat Commun. 2013 July 17; 4: 2180. Published online 2013 July 17. doi: 10.1038/ncomms3180
PMCID: PMC3759041

124: Human Parainfluenza Virus Type 2 V Protein Inhibits TRAF6-Mediated Ubiquitination of
IRF7 To Prevent TLR7- and TLR9-Dependent Interferon Induction
Yoshinori Kitagawa, Mayu Yamaguchi, Min Zhou, Machiko Nishio, Masae Itoh, Bin Gotoh
J Virol. 2013 July; 87(14): 7966–7976. doi: 10.1128/JVI.03525-12
PMCID: PMC3700191

125: Pressure-Induced Endocytic Degradation of the Saccharomyces cerevisiae Low-Affinity
Tryptophan Permease Tat1 Is Mediated by Rsp5 Ubiquitin Ligase and Functionally Redundant
PPxY Motif Proteins
Asaha Suzuki, Takahiro Mochizuki, Satoshi Uemura, Toshiki Hiraki, Fumiyoshi Abe
Eukaryot Cell. 2013 July; 12(7): 990–997. doi: 10.1128/EC.00049-13
PMCID: PMC3697464

126: MOR Is Not Enough: Identification of Novel mu-Opioid Receptor Interacting Proteins
Using Traditional and Modified Membrane Yeast Two-Hybrid Screens
Jessica Petko, Stephanie Justice-Bitner, Jay Jin, Victoria Wong, Saranya Kittanakom, Thomas N.
Ferraro, Igor Stagljar, Robert Levenson
PLoS One. 2013; 8(6): e67608. Published online 2013 June 28.
doi: 10.1371/journal.pone.0067608
PMCID: PMC3695902

127: Decoupling the Role of Ubiquitination for the Dislocation Versus Degradation of Major
Histocompatibility Complex (MHC) Class I Proteins during Endoplasmic Reticulum-associated
Degradation (ERAD)
Xiaoli Wang, Y. Y. Lawrence Yu, Nancy Myers, Ted H. Hansen
J Biol Chem. 2013 August 9; 288(32): 23295–23306. Published online 2013 June 25.
doi: 10.1074/jbc.M113.482018
PMCID: PMC3743500

128: 53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark
Amélie Fradet-Turcotte, Marella D. Canny, Cristina Escribano-Díaz, Alexandre Orthwein,
Charles C.Y. Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M.
Noordermeer, Frank Sicheri, Daniel Durocher
Nature. Author manuscript; available in PMC 2014 March 15.Published in final edited form as:
Nature. 2013 July 4; 499(7456): 50–54. Published online 2013 June 12.
doi: 10.1038/nature12318
PMCID: PMC3955401

129: Stabilization of the μ-Opioid Receptor by Truncated Single Transmembrane Splice
Variants through a Chaperone-like Action
Jin Xu, Ming Xu, Taylor Brown, Grace C. Rossi, Yasmin L. Hurd, Charles E. Inturrisi, Gavril
W. Pasternak, Ying-Xian Pan
J Biol Chem. 2013 July 19; 288(29): 21211–21227. Published online 2013 June 11.
doi: 10.1074/jbc.M113.458687
PMCID: PMC3774389

130: A Novel Role of the N Terminus of Budding Yeast Histone H3 Variant Cse4 in UbiquitinMediated Proteolysis
Wei Chun Au, Anthony R. Dawson, David W. Rawson, Sara B. Taylor, Richard E. Baker,
Munira A. Basrai
Genetics. 2013 June; 194(2): 513–518. doi: 10.1534/genetics.113.149898
PMCID: PMC3664860

131: NEW TOOLS FOR THE BRAINBOW TOOLBOX
Dawen Cai, Kimberly B. Cohen, Tuanlian Luo, Jeff W. Lichtman, Joshua R. Sanes
Nat Methods. Author manuscript; available in PMC 2013 November 5.Published in final edited
form as: Nat Methods. 2013 May 5; 10(6): 540–547. Published online 2013 May 5.
doi: 10.1038/nmeth.2450
PMCID: PMC3713494

132: Preliminary X-ray crystallographic studies of an N-terminal domain of unknown function
from a putative glycosyltransferase from Streptococcus parasanguinis
Hua Zhang, Fan Zhu, Lei Ding, Meixian Zhou, Ren Wu, Hui Wu
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1; 69(Pt 5): 520–523. Published
online 2013 April 30. doi: 10.1107/S1744309113007161
PMCID: PMC3660891

133: Analysis of SUMOylated proteins using SUMO-traps
Elisa Da Silva-Ferrada, Wendy Xolalpa, Valérie Lang, Fabienne Aillet, Itziar Martin-Ruiz,
Carlos F. de la Cruz-Herrera, Fernando Lopitz-Otsoa, Arkaitz Carracedo, Seth J. Goldenberg,
Carmen Rivas, Patrick England, Manuel S. Rodríguez
Sci Rep. 2013; 3: 1690. Published online 2013 April 22. doi: 10.1038/srep01690
PMCID: PMC3631770

134: Single-molecule sorting reveals how ubiquitylation affects substrate recognition and
activities of FBH1 helicase
Tokiha Masuda-Ozawa, Trish Hoang, Yeon-Soo Seo, Lin-Feng Chen, Maria Spies
Nucleic Acids Res. 2013 April; 41(6): 3576–3587. Published online 2013 February 6.
doi: 10.1093/nar/gkt056
PMCID: PMC3616717

135: Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikinsignaling KAI2 and strigolactone-signaling DWARF14
Li-Hua Zhao, X Edward Zhou, Zhong-Shan Wu, Wei Yi, Yong Xu, Suling Li, Ting-Hai Xu, Yue
Liu, Run-Ze Chen, Amanda Kovach, Yangyong Kang, Li Hou, Yuanzheng He, Cen Xie,
Wanling Song, Dafang Zhong, Yechun Xu, Yonghong Wang, Jiayang Li, Chenghai Zhang,
Karsten Melcher, H Eric Xu
Cell Res. 2013 March; 23(3): 436–439. Published online 2013 February 5.
doi: 10.1038/cr.2013.19
PMCID: PMC3587710

136: Unfoldase-mediated protein translocation through an α-hemolysin nanopore
Jeff Nivala, Douglas B Marks, Mark Akeson
Nat Biotechnol. Author manuscript; available in PMC 2013 September 13.Published in final
edited form as: Nat Biotechnol. 2013 March; 31(3): 247–250. Published online 2013 February 3.
doi: 10.1038/nbt.2503
PMCID: PMC3772521

137: Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to
the cytosol for recognition by DNA sensors
Kristy A. Horan, Kathrine Hansen, Martin R. Jakobsen, Christian K. Holm, Stine Søby, Leonie
Unterholzner, Mikayla Thompson, John A. West, Marie B. Iversen, Simon B. Rasmussen, Svend
Ellermann-Eriksen, Evelyn Kurt-Jones, Santo Landolfo, Blossom Damania, Jesper Melchjorsen,
Andrew G. Bowie, Katherine A. Fitzgerald, Søren R. Paludan
J Immunol. Author manuscript; available in PMC 2014 March 1.Published in final edited form
as: J Immunol. 2013 March 1; 190(5): 2311–2319. Published online 2013 January 23.
doi: 10.4049/jimmunol.1202749
PMCID: PMC3578088

138: Trypanosoma brucei S-Adenosylmethionine Decarboxylase N Terminus Is Essential for
Allosteric Activation by the Regulatory Subunit Prozyme
Nahir Velez, Chad A. Brautigam, Margaret A. Phillips
J Biol Chem. 2013 February 15; 288(7): 5232–5240. Published online 2013 January 3.
doi: 10.1074/jbc.M112.442475
PMCID: PMC3576127

139: MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin
signaling
Jae-Sung Yi, Jun Sub Park, Young-Mi Ham, Nga Nguyen, Na-Rae Lee, Jin Hong, Bong-Woo
Kim, Hyun Lee, Chang-Seok Lee, Byung-Cheon Jeong, Hyun Kyu Song, Hana Cho, Yoon Ki
Kim, Jae-Seon Lee, Kyong-Soo Park, Hakseob Shin, Inho Choi, Seung Hee Lee, Woo Jin Park,
Shi-Young Park, Cheol Soo Choi, Peihui Lin, Malith Karunasiri, Tao Tan, Pu Duann, Hua Zhu,
Jianjie Ma, Young-Gyu Ko
Nat Commun. Author manuscript; available in PMC 2014 March 4.Published in final edited
form as: Nat Commun. 2013; 4: 2354. doi: 10.1038/ncomms3354
PMCID: PMC3941707

140: Small ubiquitin-like modifying protein isopeptidase assay based on poliovirus RNA
polymerase activity
Jamie J. Arnold, Alejandro Bernal, Uzo Uche, David E. Sterner, Tauseef R. Butt, Craig E.
Cameron, Michael R. Mattern
Anal Biochem. Author manuscript; available in PMC 2007 November 26.Published in final
edited form as: Anal Biochem. 2006 March 15; 350(2): 214–221. Published online 2005
November 17. doi: 10.1016/j.ab.2005.11.001
PMCID: PMC2094218

141: Androgen receptor degradation by the E3 ligase CHIP modulates mitotic arrest in prostate
cancer cells
S Sarkar, DL Brautigan, SJ Parsons, JM Larner
Oncogene. Author manuscript; available in PMC 2014 January 23.Published in final edited form
as: Oncogene. 2014 January 2; 33(1): 26–33. Published online 2012 December 17.
doi: 10.1038/onc.2012.561
PMCID: PMC3899837

142: The Interaction of Prp2 with a Defined Region of the Intron Is Required for the First
Splicing Reaction
Hsueh-Lien Liu, Soo-Chen Cheng
Mol Cell Biol. 2012 December; 32(24): 5056–5066. doi: 10.1128/MCB.01109-12
PMCID: PMC3510548

143: The Ω-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic
function
Troy A. Johnson, Todd Holyoak
Biochemistry. Author manuscript; available in PMC 2013 November 27.Published in final edited
form as: Biochemistry. 2012 November 27; 51(47): 9547–9559. Published online 2012
November 14. doi: 10.1021/bi301278t
PMCID: PMC3525453

144: MultiDsk: A Ubiquitin-Specific Affinity Resin
Marcus D. Wilson, Marco Saponaro, Mathias A. Leidl, Jesper Q. Svejstrup
PLoS One. 2012; 7(10): e46398. Published online 2012 October 3.
doi: 10.1371/journal.pone.0046398
PMCID: PMC3463603

145: Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome
Activation
Christine Juliana, Teresa Fernandes-Alnemri, Seokwon Kang, Andrew Farias, Fengsong Qin,
Emad S. Alnemri
J Biol Chem. 2012 October 19; 287(43): 36617–36622. Published online 2012 September 4.
doi: 10.1074/jbc.M112.407130
PMCID: PMC3476327

146: Polyubiquitin Is Required for Growth, Development and Pathogenicity in the Rice Blast
Fungus Magnaporthe oryzae
Yeonyee Oh, William L. Franck, Sang-Oh Han, Angela Shows, Emine Gokce, David C.
Muddiman, Ralph A. Dean
PLoS One. 2012; 7(8): e42868. Published online 2012 August 10.
doi: 10.1371/journal.pone.0042868
PMCID: PMC3416782

147: Cathepsin G-regulated Release of Formyl Peptide Receptor Agonists Modulate Neutrophil
Effector Functions
Josh C. Woloszynek, Ying Hu, Christine T. N. Pham
J Biol Chem. 2012 October 5; 287(41): 34101–34109. Published online 2012 August 9.
doi: 10.1074/jbc.M112.394452
PMCID: PMC3464519

148: Activity of the tetrapyrrole regulator CrtJ is controlled by oxidation of a redox active
cysteine located in the DNA binding domain
Zhuo Cheng, Jiang Wu, Aaron Setterdahl, Khalilah Reddie, Kate Carroll, Loubna A. Hammad,
Jonathan A. Karty, Carl E. Bauer
Mol Microbiol. Author manuscript; available in PMC 2013 August 1.Published in final edited
form as: Mol Microbiol. 2012 August; 85(4): 734–746. Published online 2012 July 16.
doi: 10.1111/j.1365-2958.2012.08135.x
PMCID: PMC3418406

149: TP-RT Domain Interactions of Duck Hepatitis B Virus Reverse Transcriptase in cis and in
trans during Protein-Primed Initiation of DNA Synthesis In Vitro
Rajeev K. Boregowda, Christina Adams, Jianming Hu
J Virol. 2012 June; 86(12): 6522–6536. doi: 10.1128/JVI.00086-12
PMCID: PMC3393569

150: Functional Dissection of N-Acetylglutamate Synthase (ArgA) of Pseudomonas aeruginosa
and Restoration of Its Ancestral N-Acetylglutamate Kinase Activity
Enea Sancho-Vaello, María L. Fernández-Murga, Vicente Rubio
J Bacteriol. 2012 June; 194(11): 2791–2801. doi: 10.1128/JB.00125-12
PMCID: PMC3370605

151: Specific Residues of a Conserved Domain in the N Terminus of the Human
Cytomegalovirus pUL50 Protein Determine Its Intranuclear Interaction with pUL53
Jens Milbradt, Sabrina Auerochs, Madhumati Sevvana, Yves A. Muller, Heinrich Sticht,
Manfred Marschall
J Biol Chem. 2012 July 6; 287(28): 24004–24016. Published online 2012 May 15.
doi: 10.1074/jbc.M111.331207
PMCID: PMC3390675

152: In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus
Polymerase
Scott A. Jones, Rajeev Boregowda, Thomas E. Spratt, Jianming Hu
J Virol. 2012 May; 86(9): 5134–5150. doi: 10.1128/JVI.07137-11Correction in: J Virol. 2013
November; 87(22): 12504.
PMCID: PMC3347376

153: Structural and Biochemical Characterization of Human Mitochondrial Branched-chain αKetoacid Dehydrogenase Phosphatase
R. Max Wynn, Jun Li, Chad A. Brautigam, Jacinta L. Chuang, David T. Chuang
J Biol Chem. 2012 March 16; 287(12): 9178–9192. Published online 2012 January 30.
doi: 10.1074/jbc.M111.314963
PMCID: PMC3308798

154: Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using
SILAC-based quantitative proteomics
Wei Yang, J. Will Thompson, Zhengfeng Wang, Liangli Wang, Huaxin Sheng, Matthew W.
Foster, M. Arthur Moseley, Wulf Paschen
J Proteome Res. Author manuscript; available in PMC 2013 April 17.Published in final edited
form as: J Proteome Res. 2012 February 3; 11(2): 1108–1117. Published online 2011 December
1. doi: 10.1021/pr200834f
PMCID: PMC3628696

155: Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the
Protein and Peptide Levels
Kimberly A. Lee, Lisa P. Hammerle, Paul S. Andrews, Matthew P. Stokes, Tomas Mustelin,
Jeffrey C. Silva, Roy A. Black, John R. Doedens
J Biol Chem. 2011 December 2; 286(48): 41530–41538. Published online 2011 October 10.
doi: 10.1074/jbc.M111.248856
PMCID: PMC3308864

156: The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular
regulation
Etienne Caron, Krystel Vincent, Marie-Hélène Fortier, Jean-Philippe Laverdure, Alexandre
Bramoullé, Marie-Pierre Hardy, Grégory Voisin, Philippe P Roux, Sébastien Lemieux, Pierre
Thibault, Claude Perreault
Mol Syst Biol. 2011; 7: 533. Published online 2011 September 27. doi: 10.1038/msb.2011.68
PMCID: PMC3202804

157: Crystal Structures of Histone and p53 Methyltransferase SmyD2 Reveal a Conformational
Flexibility of the Autoinhibitory C-Terminal Domain
Yuanyuan Jiang, Nualpun Sirinupong, Joseph Brunzelle, Zhe Yang
PLoS One. 2011; 6(6): e21640. Published online 2011 June 28.
doi: 10.1371/journal.pone.0021640
PMCID: PMC3125274

158: The Ubiquitin-Specific Protease USP34 Regulates Axin Stability and Wnt/β-Catenin
Signaling
Tony T. H. Lui, Celine Lacroix, Syed M. Ahmed, Seth J. Goldenberg, Craig A. Leach, Avais M.
Daulat, Stephane Angers
Mol Cell Biol. 2011 May; 31(10): 2053–2065. doi: 10.1128/MCB.01094-10
PMCID: PMC3133363

159: Comparison of SUMO fusion technology with traditional gene fusion systems: Enhanced
expression and solubility with SUMO
Jeffrey G. Marblestone, Suzanne C. Edavettal, Yiting Lim, Peter Lim, Xun Zuo, Tauseef R. Butt
Protein Sci. 2006 January; 15(1): 182–189. doi: 10.1110/ps.051812706
PMCID: PMC2242369

160: Immunization with a ZmpB-Based Protein Vaccine Could Protect against Pneumococcal
Diseases in Mice
Yi Gong, Wenchun Xu, Yali Cui, Xuemei Zhang, Run Yao, Dairong Li, Hong Wang, Yujuan
He, Ju Cao, Yibing Yin
Infect Immun. 2011 February; 79(2): 867–878. Published online 2010 November 22.
doi: 10.1128/IAI.00717-10
PMCID: PMC3028838

161: c-Abl Phosphorylation of Mdm2 Facilitates Mdm2-Mdmx Complex Formation
David L. Waning, Jason A. Lehman, Christopher N. Batuello, Lindsey D. Mayo
J Biol Chem. 2011 January 7; 286(1): 216–222. Published online 2010 November 16.
doi: 10.1074/jbc.M110.183012
PMCID: PMC3012977

162: The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylationdependent manner
Damien Garbett, David P. LaLonde, Anthony Bretscher
J Cell Biol. 2010 October 18; 191(2): 397–413. doi: 10.1083/jcb.201004115
PMCID: PMC2958488

163: Crystal Structure of Cardiac-specific Histone Methyltransferase SmyD1 Reveals Unusual
Active Site Architecture
Nualpun Sirinupong, Joseph Brunzelle, Jun Ye, Ali Pirzada, Lindsey Nico, Zhe Yang
J Biol Chem. 2010 December 24; 285(52): 40635–40644. Published online 2010 October 12.
doi: 10.1074/jbc.M110.168187
PMCID: PMC3003362

164: Isolation of SPINK6 in Human Skin: SELECTIVE INHIBITOR OF KALLIKREINRELATED PEPTIDASES
Ulf Meyer-Hoffert, Zhihong Wu, Tomasz Kantyka, Jan Fischer, Ties Latendorf, Britta
Hansmann, Joachim Bartels, Yinghong He, Regine Gläser, Jens-Michael Schröder
J Biol Chem. 2010 October 15; 285(42): 32174–32181. Published online 2010 July 28.
doi: 10.1074/jbc.M109.091850
PMCID: PMC2952218

165: The structure of FANCL, the catalytic subunit of the Fanconi Anemia core complex
Ambrose R. Cole, Laurence P.C. Lewis, Helen Walden
Nat Struct Mol Biol. Author manuscript; available in PMC 2010 September 1.Published in final
edited form as: Nat Struct Mol Biol. 2010 March; 17(3): 294–298. Published online 2010
February 14. doi: 10.1038/nsmb.1759
PMCID: PMC2929457

166: A Gate-Latch-Lock Mechanism for Hormone Signaling by Abscisic Acid Receptors
Karsten Melcher, Ley-Moy Ng, X. Edward Zhou, Fen-Fen Soon, Yong Xu, Kelly M. SuinoPowell, Sang-Youl Park, Joshua J. Weiner, Hiroaki Fujii, Viswanathan Chinnusamy, Amanda
Kovach, Jun Li, Yonghong Wang, Jiayang Li, Francis C. Peterson, Davin R. Jensen, Eu-Leong
Yong, Brian F. Volkman, Sean R. Cutler, Jian-Kang Zhu, H. Eric Xu
Nature. Author manuscript; available in PMC 2010 June 3.Published in final edited form as:
Nature. 2009 December 3; 462(7273): 602–608. doi: 10.1038/nature08613
PMCID: PMC2810868

167: Pivotal Role of the C-terminal DW-motif in Mediating Inhibition of Pyruvate
Dehydrogenase Kinase 2 by Dichloroacetate
Jun Li, Masato Kato, David T. Chuang
J Biol Chem. 2009 December 4; 284(49): 34458–34467. Published online 2009 October 15.
doi: 10.1074/jbc.M109.065557
PMCID: PMC2797213

168: Distinct Amino Termini of Two Human HCS Isoforms Influence Biotin Acceptor Substrate
Recognition
Maria Ingaramo, Dorothy Beckett
J Biol Chem. 2009 November 6; 284(45): 30862–30870. Published online 2009 September 9.
doi: 10.1074/jbc.M109.046201
PMCID: PMC2781485

169: Structural Studies of Soybean Calmodulin Isoform 4 Bound to the Calmodulin-binding
Domain of Tobacco Mitogen-activated Protein Kinase Phosphatase-1 Provide Insights into a
Sequential Target Binding Mode
Hiroaki Ishida, Mario Rainaldi, Hans J. Vogel
J Biol Chem. 2009 October 9; 284(41): 28292–28305. Published online 2009 August 10.
doi: 10.1074/jbc.M109.025080
PMCID: PMC2788880

170: Stabilization of Peptide Vesicles by Introducing Inter-Peptide Disulfide Bonds
Albert J. van Hell, Daan J. A. Crommelin, Wim E. Hennink, Enrico Mastrobattista
Pharm Res. 2009 September; 26(9): 2186–2193. Published online 2009 July 7.
doi: 10.1007/s11095-009-9933-z
PMCID: PMC2719749

171: Cdc7p-Dbf4p Regulates Mitotic Exit by Inhibiting Polo Kinase
Charles T. Miller, Carrie Gabrielse, Ying-Chou Chen, Michael Weinreich
PLoS Genet. 2009 May; 5(5): e1000498. Published online 2009 May 29.
doi: 10.1371/journal.pgen.1000498
PMCID: PMC2682205

172: Characterization of purified Sindbis Virus nsP4 RNA-dependent RNA Polymerase activity
in vitro
Jon K. Rubach, Brian R. Wasik, Jonathan C. Rupp, Richard J. Kuhn, Richard W. Hardy, Janet L.
Smith
Virology. Author manuscript; available in PMC 2011 June 3.Published in final edited form as:
Virology. 2009 February 5; 384(1): 201–208. Published online 2008 November 25.
doi: 10.1016/j.virol.2008.10.030
PMCID: PMC3107704

173: A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within
homonucleotide runs in yeast.
J M Kirchner, H Tran, M A Resnick
Genetics. 2000 August; 155(4): 1623–1632.
PMCID: PMC1461198

174: Norovirus Proteinase-Polymerase and Polymerase Are Both Active Forms of RNADependent RNA Polymerase
Gaël Belliot, Stanislav V. Sosnovtsev, Kyeong-Ok Chang, Vijay Babu, Uzo Uche, Jamie J.
Arnold, Craig E. Cameron, Kim Y. Green
J Virol. 2005 February; 79(4): 2393–2403. doi: 10.1128/JVI.79.4.2393-2403.2005
PMCID: PMC546540

175: ClpS modulates but is not essential for bacterial N-end rule degradation
Kevin H. Wang, Robert T. Sauer, Tania A. Baker
Genes Dev. 2007 February 15; 21(4): 403–408. doi: 10.1101/gad.1511907
PMCID: PMC1804329

176: Genetic factors affecting the impact of DNA polymerase delta proofreading activity on
mutation avoidance in yeast.
H T Tran, N P Degtyareva, D A Gordenin, M A Resnick
Genetics. 1999 May; 152(1): 47–59.
PMCID: PMC1460598

177: Ni W, Xu SL, Tepperman JM, Stanley DJ, Maltby DA, Gross JD, Burlingame AL, Wang
ZY, Quail PH. A mutually assured destruction mechanism attenuates lightsignaling in
Arabidopsis. Science. 2014 Jun 6;344(6188):1160-4. doi:10.1126/science.1250778. PubMed
PMID: 24904166; PubMed Central PMCID: PMC4414656.

178: Fradet-Turcotte A, Canny MD, Escribano-Díaz C, Orthwein A, Leung CC, Huang H,
Landry MC, Kitevski-LeBlanc J, Noordermeer SM, Sicheri F, Durocher D. 53BP1 is a reader of
the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature. 2013 Jul4;499(7456):50-4. doi:
10.1038/nature12318. Epub 2013 Jun 12. PubMed PMID:23760478; PubMed Central PMCID:
PMC3955401.

179: Bozza WP, Liang Q, Gong P, Zhuang Z. Transient kinetic analysis of USP2-catalyzed
deubiquitination reveals a conformational rearrangement in the K48-linked diubiquitin substrate.
Biochemistry. 2012 Dec 18;51(50):10075-86. doi:10.1021/bi3009104. Epub 2012 Dec 4.
PubMed PMID: 23211065; PubMed Central PMCID:

180: Hjerpe, R., Aillet, F., Lopitz-Otsoa, F., Lang, V., England, P., and Rodriques, M.S. (2009)
Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding
entitities. EMBO Rep. 10,1250-1258.