Specifications
One of the most potent and selective proteasome inhibitors, Epoxomycin inhibits all three activities of the proteasome. Epoxomicin (100 nM) results in a 30-fold increase in the levels of p53 protein, a known target of the proteasome, in HUVECs. Epoxomicin (10 μM) results in the accumulation of ubiquitinated proteins in HeLa cells. Epoxomicin (10 μM) inhibits IκBα degradation by 10-fold in HeLa cells.
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Info
| Purity | >99.0% by HPLC |
| Quantity | 100 ug |
| Molecular Weight | 554.72 Da |
| Physical State | Lyophilized powder |
| Solubility | DMSO (10 mg/mL) |
| CAS No. | 134381-21-8 |
| Storage | 4°C, (-20°C Long term). The product can be shipped at room temperature. |
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