Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9629: IU1

LifeSensors SI9629 is a selective, reversible, cell-permeable inhibitor of proteasome-associated DUB USP14 with IC50 below 4 µM, ideal for proteasome research.

$233.00

SKU SI-9629-0010 Categories DUB inhibitors, Proteasome Inhibitors, Small Molecule Modulators and PROTACs

In stock

Product Advantages

Applications

Inhibition of USP14
Cell biology
Drug discovery
Benefits: cell-permeable

IU1 is a cell-permeable, reversible, and selective inhibitor of the proteasome-associated DUB USP14 (IC50 < 4 µM). IU1 enhances proteasome activity and substrate proteolysis. IU1 promotes cell survival under stress conditions and selectively stimulates ubiquitin-dependent protein degradation in vitro.

Info

Purity	> 98% (TLC), NMR (Conforms)
Quantity	10 mg
Molecular Weight	300.4 Da
Physical State	Beige powder
Solubility	DMSO (30 mg/mL)
CAS No.	314245-33-5
Storage	4°C, (-20°C Long term). The product can be shipped at room temperature.

Datasheet

Datasheet

Applications

Inhibition of USP14
Cell biology
Drug discovery
Benefits: cell-permeable

send us a message for pricing

CONTACT INFORMATION

Phone (Office)

610.644.8845

SEND EMAIL

info@lifesensors.com

VISIT ANYTIME

271 Great Valley Parkway Malvern, PA 19355

More from This Category

SI9649: 1,10 phenanthroline

LifeSensors SI9649 (1,10-Phenanthroline) is a chelator with high affinity for divalent metal ions, used in biochemical research for metal ion binding and inhibition studies.

SI9740: Celastrol

LifeSensors SI9740 is a specialized phospho-ubiquitin chain derivative designed for advanced research in ubiquitin signaling and protein regulation pathways.

SI9810: PYR-41 conjugating enzyme inhibitor

LifeSensors SI9810 (PYR-41) is a cell-permeable, irreversible inhibitor of ubiquitin-activating enzyme E1, with IC50 < 10 µM, used in research on protein ubiquitination and degradation.

SI9639: LDN-57444, DUB inhibitor

LifeSensors SI9639 is a potent, selective inhibitor of USP7 deubiquitinase, used in research to study protein regulation and cancer therapy development.

PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.

Discovery

About lifesensors

Resources

Address: 271 Great Valley Parkway Malvern, PA 19355