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Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI4812: DUB-Resistant K48-Linked Di-Ubiquitin

SKU SI-4812-0100 Categories ,
LifeSensors’ SI4812 is a DUB-resistant K48-linked di-ubiquitin reagent designed for studying ubiquitin signaling and protease activity in biochemical research

$672.00

In stock

In stock

DUB-Resistant, K48-Linked Di-Ubiquitin (Ub2) contains an amino acid substitution near the C-terminus of the distal ubiquitin that renders it resistant to deubiquitylases (DUBs). DUB-resistant ubiquitin chains are ideal reagents for structural or binding studies with deubiquitylases or other ubiquitin binding proteins. They can also be used as inhibitors or to determine the linkage-specificity of DUBs. The product contains a K48R mutation in the distal ubiquitin and a wild-type C-terminus on the proximal ubiquitin.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 17,123.7 Da
Quantity 100µg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 1 mM EDTA
Storage -80°C, avoid freeze/thaw cycles

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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