Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.
SI0102-5µg (panel) Linear (Ub2) di-ubiquitin

SI280: Ubiquitin, Biotinylated (all lysines unmodified)

SKU SI-0280-0100 Categories , , Tag
LifeSensors’ SI280 is biotinylated ubiquitin with all lysines unmodified, ideal for studying protein ubiquitination and post-translational modifications in cellular research

$335.00

In stock

In stock

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the C-terminus of Ub and the ε-amino group of a lysine (Lys) residue on the target substrate. Ub itself has seven Lys residues (6, 11, 27, 29, 33, 48, and 63), any of which can participate in further ubiquitylation, generating polyUb chains. LifeSensors’ biotinylated ubiquitin carries a single biotin molecule attached at a defined location and unlike other biotinylated ubiquitins, avoids modification of the N-terminus, C-terminus or any of the seven Lys side chains. Therefore, this biotinylated ubiquitin has all lysines available for conjugation and can be incorporated into polyubiquitin chains of any linkage type.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 9,106.98 Da
Quantity 100µg
Concentration Variable
Formulation PBS
Storage -80°C, avoid freeze/thaw cycles
 
  • In vitro ubiquitin conjugation
  • Determination of the activity of ubiquitin conjugating enzymes
  • Unmodified N-terminus, C-terminus
  • All seven lysine residues are available for conjugation and can be incorporated into polyubiquitin chains of any linkage type

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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