Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI212: Ubiquitin-K6R

LifeSensors’ SI212: Ubiquitin-K6R is a high-quality ubiquitin K to R mutant protein, ideal for advanced polyubiquitin research and biochemical applications

$184.00

In stock

In stock

Ubiquitin-K6R is recombinant ubiquitin with a single substitution of arginine for lysine at position 6. Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can subsequently be conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This modification will ensure chains will not form at mutated lysine to arginine peptide.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 8,592 Da
Quantity 1mg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles
  • Investigation of E1-E2-E3 mediated ubiquitin ligation
  • Investigation of DUB linkage specificity

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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