SI1103: K11-Linked Tri-Ubiquitin

Increasingly, researchers are focusing on the role of poly-ubiquitin chains linked through K11. This post-translational modification has been linked to ERAD as a signal for proteasomal degradation. K11-linked chains appear to play an important role in cell cycle signaling, as they are associated with the anaphase promoting complex (APC). These tri-ubiquitin chains are generated from the enzymatic linkage of wild-type ubiquitin through lysine 11 and purified to >95% homogenity by ion exchange chromatography.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	25,656 Da
Quantity	100 µg
Concentration	Variable
Formulation	20 mM Tris pH 7.5, 150 mM NaCl, 1 mM EDTA
Storage	-80°C, avoid freeze/thaw cycles