Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI206: Ubiquitin-K33

SKU SI-0206-1000 Categories ,
LifeSensors’ SI206 is a high-purity Ubiquitin-K33 protein used for advanced research in ubiquitin signaling, proteomics, and drug discovery applications

$184.00

In stock

In stock

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This tag-free recombinant form of human ubiquitin is engineered to have all available lysines mutated to arginines, except at position 33. This molecule, therefore, can only form polyubiquitin chains of K33 linkage type.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 8,732 Da
Quantity 1mg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles
  • Characterization of proteins responsible for ubiquitin conjugation or removal
  • Ligand binding studies with ubiquitin related proteins
  • Characterization of linkage type for target protein
  • Profiling of E2/E3 interactions
  • Characterization of E3 polyubiquitylation activity
  • Native (tag free) recombinant wild-type ubiquitin

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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