AB701: Anti-SENP1core Antibody

LifeSensors AB701 is an Anti-SENP1core antibody, crucial for detecting SENP1, a SUMO isopeptidase linked to prostate cancer development. Ideal for WB applications.

$370.00

In stock

SENP1 is a SUMO isopeptidase that plays a critical role in the development of prostate cancer. SENP1 is overexpressed in prostate cancer samples. Overexpression of SENP1 in the prostate of mice leads to the development of prostatic intraepithelial neoplasia at an early stage. Consistent with the role of SENP1 in prostate cancer, it has demonstrated that overexpression of SENP1 enhances androgen-receptor mediated transcription. Inactivation of SENP1 in mice by retroviral insertion mutation is embryonic lethal (e12.5-e14.5) and leads to an increase in the steady state levels of SUMOylated forms of a number of proteins. Depletion of SENP1 levels in PC3 cells by RNAi leads to a decrease in cyclin D1 expression.

Info

Host	Chicken
Quantity	250µg
Concentration	Variable
Storage	-20°C; Do not aliquot

Datasheet

Applications

Applications: Western Blotting
Recommended Antibody Dilutions: Robust detection of 100ng of recombinant protein was possible when antibody was used at a final concentration of 5μg/mL

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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AB701: Anti-SENP1core Antibody

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