SU202: SUMO-2

LifeSensors SU202 is a SUMO fusion expression system designed to enhance protein yield and solubility, enabling cost-effective, scalable purification with efficient tag removal for diverse expression hosts.

$234.00

SKU SU-0202-0500 Category Sumo Derivatives Chain

In stock

Product Advantages

Applications

For use in conjunction assays using SUMO E1 (Cat. # SU101) and UBE2I (Ubc9; Cat. # UB228H). SUMO can be conjugated to consensus sequences (ψ-K-X-D/E; ψ is any large hydrophobic residue and X is any amino acid) in vitro independent of an E3 enzyme.

Benefits

Inclusion of a SUMO E3 can increase the rate of conjugation and/or direct SUMOylation to nonconsensus sites.

Human recombinant SUMO-2 is produced in E. coli and purified to >95% homogeneity. This protein contains no extraneous tags. Vertebrates express three SUMO homologs, SUMO-1 and the closely related SUMO-2/3, which can be conjugated to substrate proteins in a manner analogous to the ubiquitin system1-3. Although a fourth SUMO (SUMO-4) has been identified in the genome, it may be an unexpressed pseudogene.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	10,477.7 Da
Quantity	500 µg
Concentration	Variable
Formulation	Phosphate Buffered Saline (pH 7.4)
Storage	-80°C, avoid freeze/thaw cycles

Datasheet

Datasheet

Applications

For use in conjunction assays using SUMO E1 (Cat. # SU101) and UBE2I (Ubc9; Cat. # UB228H). SUMO can be conjugated to consensus sequences (ψ-K-X-D/E; ψ is any large hydrophobic residue and X is any amino acid) in vitro independent of an E3 enzyme.

Benefits