Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI420: hSUMO1-AMC

SKU SI-0420-0050 Category
LifeSensors SI420 (hSUMO1-AMC) is a fluorogenic substrate for SUMO1 protease assays, enabling sensitive detection of SUMO1-specific enzymatic activity in research.

$540.00

In stock

In stock

SUMO1-AMC is prepared via the conjugation of 7-amino-4-methylcoumarin (AMC) to the C-terminal Gly of human SUMO1. This conjugation quenches the intrinsic fluorescence of AMC. Upon incubation with a protease recognizing SUMOs, such as Senp1 or Senp2, AMC is released and the increase in fluorescence at 460 nm (excitation at 380 nm) can be measured. The enhanced purity of SUMO1-AMC compared to that of other commercial vendors leads to a greater signal to noise ratio. This protein contains no extraneous tags.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 11,142.5 Da
Quantity 50µg
Concentration Variable
Formulation Lyophilized Powder
Storage -80°C, avoid freeze/thaw cycles

Used for determining the activity and specificity of SUMO-specific hydrolases, and for high-throughput screening for modulators of deSUMOylase activity

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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