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DB501: USP2 Core

SKU DB-0501-0025 Categories , Tags ,
LifeSensors DB501 is the USP2 core enzyme, a catalytic domain effective in cleaving polyubiquitin chains linked via K48 and K63, used for deubiquitinase activity assays

$203.00

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In stock

USP2 core represents the common catalytic core domain of the two isoforms of USP2 (Ubiquitin specific protease 2), USP2a and USP2b. It deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. USP2 plays a role in the G1/S cell-cycle progression in normal and cancer cells.

Info

Species Human
Source E. coli
Tag His6
Molecular Weight 40 kDa
Quantity 25µg
Concentration Variable
Formulation 50 mM Tris pH 8.0, 150 mM NaCl, 5 mM DTT, 10% Glycerol
Storage -80°C, avoid freeze/thaw cycles

This enzyme is active in the Ub-CHOP Assay.

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