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AB505: Anti-USP14 Antibody
Lifesensors AB505 is a high-quality anti-USP14 antibody used for detecting ubiquitin-specific peptidase 14 in research on protein degradation and neurodegeneration. It supports studies on proteasome function and ubiquitin signaling pathways.
Recommended Antibody Dilutions: Robust detection of 50ung of recombinant protein was possible when antibody was used at a final concentration of 8.14μg/mL
USP14 is a ubiquitin specific protease that associates with the proteasome. This association with the proteasome has been shown to enhance the enzymatic activity of the proteasome. Recent studies have demonstrated that the expression of USP14 in certain cancers correlates with metastasis. Using a chemical probe, it has been shown that USP14 can interact with ISG15, a ubiquitin-like protein.
Recommended Antibody Dilutions: Robust detection of 50ung of recombinant protein was possible when antibody was used at a final concentration of 8.14μg/mL