UB317A: Parkin (Phosphorylated)

Encoded by the PARK2 gene, the E3 ligase Parkin is part of the multi-protein E3 complex that encodes substrate proteins for degradation in the Ubiquitin-Proteasome Pathway. The precise function of this protein is unknown; however, mutations in this gene are known to cause a familial form of Parkinson’s disease known as autosomal recessive juvenile Parkinson’s disease (AR-JP). Parkin is described to be necessary for mitophagy (autophagy of mitochondria).

Info

Species	Human
Source	E. coli
Tag	His6SUMO
Molecular Weight	64 kDa
Quantity	25 µg
Concentration	Variable
Formulation
Storage	-80°C, avoid freeze/thaw cycles